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Noninvasive assessment of mental, physical and respiratory stressors on cardiovascular function

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TitleInfo (displayLabel = Citation Title); (type = uniform)
Title
Noninvasive assessment of mental, physical and respiratory stressors on cardiovascular function
Name (ID = NAME001); (type = personal)
NamePart (type = family)
Looi
NamePart (type = given)
Jennifer C.
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Jennifer C. Looi
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author
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Moghe
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Prabhas
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Advisory Committee
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Prabhas V. Moghe
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chair
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Li
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John
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Advisory Committee
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John K-J. Li
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internal member
Name (ID = NAME004); (type = personal)
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Shoane
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George
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Advisory Committee
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George K. Shoane
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internal member
Name (ID = NAME005); (type = personal)
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Drzewiecki
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Gary
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Advisory Committee
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Gary M. Drzewiecki
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internal member
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Rutgers University
Role
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degree grantor
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Graduate School - New Brunswick
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school
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Text
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theses
OriginInfo
DateCreated (qualifier = exact)
2007
DateOther (qualifier = exact); (type = degree)
2007
Language
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English
PhysicalDescription
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electronic
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application/pdf
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text/xml
Extent
ix, 91 pages
Abstract
Stress is encountered in daily life from relationships with people, work obligations, and our environment. Often viewed from the realm of the social sciences, this field of study was perceived to be limited to descriptive measures, which only captured information discretely. As medicine started to investigate the biological ramifications of the stress response, it elevated the importance of stress as a precursor to several chronic diseases, which manifest both physically and mentally. As a result, many sub-areas of research have emerged to examine the relationship of stress to various systems within the human body, which include the endocrine, cardiovascular, respiratory systems. Growing understanding of the biological realities of stress will help disentangle the multiple connotations of stress. It can aid in producing better targeted medications and treatments. This thesis compared three types of stressors and sought to determine which cardiovascular parameters were most sensitive to stress. Young volunteers were subjected to mental, physical and respiratory stressors while their variability of heart rate, blood pressure and blood flow velocity were measured to examine the role of stress on the cardiovascular system. From comparisons between the rest and different stressor interventions for each subject, statistics from paired T tests show significant differences exist between each stressor and rest phase. In addition, testing of the null hypothesis against T wave amplitude, QT interval, R-P onset, frequency, beats per minute, change in blood pressure and change in blood flow velocity reveal the most sensitive cardiovascular parameters are frequency, beats per minute, blood pressure and flow velocity. These cardiovascular parameters can be used as indicators to study the course of coronary artery disease, myocardial infarction, atherosclerosis and hypertension. The present study can be improved by including measurement of glucose and stress hormones during stressor interventions to enhance our understanding of the stress response. This would aid in studying other stress-induced diseases outside the realm of the cardiovascular system.
Note (type = degree)
M.S.
Note (type = bibliography)
Includes bibliographical references (p. 89-91).
Subject (ID = SUBJ1); (authority = RUETD)
Topic
Biomedical Engineering
Subject (ID = SUBJ2); (authority = ETD-LCSH)
Topic
Stress (Physiology)
Subject (ID = SUBJ3); (authority = ETD-LCSH)
Topic
Heart--Effect of stress on
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Title
Graduate School - New Brunswick Electronic Theses and Dissertations
Identifier (type = local)
rucore19991600001
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http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.15761
Identifier
ETD_385
Location
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NjNbRU
Identifier (type = doi)
doi:10.7282/T31N81K1
Genre (authority = ExL-Esploro)
ETD graduate
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The author owns the copyright to this work.
Copyright
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Copyright protected
Availability
Status
Open
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Name
Jennifer Looi
Role
Copyright holder
Affiliation
Rutgers University. Graduate School - New Brunswick
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Non-exclusive ETD license
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License
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Author Agreement License
Detail
I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
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