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Multiphysics computations on celluar interaction in complex geometries and vortex-accelerated vorticity deposition in Richtmyer-Meshkov instability

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TitleInfo (displayLabel = Citation Title); (type = uniform)
Title
Multiphysics computations on celluar interaction in complex geometries and vortex-accelerated vorticity deposition in Richtmyer-Meshkov instability
Name (ID = NAME001); (type = personal)
NamePart (type = family)
Peng
NamePart (type = given)
Gaozhu
DisplayForm
Gaozhu Peng
Role
RoleTerm (authority = RULIB)
author
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NamePart (type = family)
Zabusky
NamePart (type = given)
Norman
Affiliation
Advisory Committee
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Norman Zabusky
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chair
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NamePart (type = family)
Bagchi
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Prosenjit
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Advisory Committee
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Prosenjit Bagchi
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internal member
Name (ID = NAME004); (type = personal)
NamePart (type = family)
Zebib
NamePart (type = given)
Abdelfattah
Affiliation
Advisory Committee
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Abdelfattah Zebib
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internal member
Name (ID = NAME005); (type = personal)
NamePart (type = family)
Craelius
NamePart (type = given)
William
Affiliation
Advisory Committee
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William Craelius
Role
RoleTerm (authority = RULIB)
outside member
Name (ID = NAME006); (type = corporate)
NamePart
Rutgers University
Role
RoleTerm (authority = RULIB)
degree grantor
Name (ID = NAME007); (type = corporate)
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Graduate School - New Brunswick
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school
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Text
Genre (authority = marcgt)
theses
OriginInfo
DateCreated (qualifier = exact)
2008
DateOther (qualifier = exact); (type = degree)
2008-01
Language
LanguageTerm
English
PhysicalDescription
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electronic
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application/pdf
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text/xml
Extent
xx, 166 pages
Abstract
The cellular interactions during leukocyte margination and adhesion cascade in
cardiovascular microcirculations are multi-scale and multiphysics phenomena, involving fluid flow, cell mechanics, chemical reaction kinetics and transport, fluid structure interaction. The vascular network in vivo has rather complicated topology unlike straight and flat channels and pipes where most biological experiments in vitro and numerical simulations are carried. A computational framework is formulated towards a goal of building a virtual blood vessel system to simulate the hydrodynamic and kinetic interactions of blood cells in complex vascular geometries, including vascular network bifurcations and irregular shapes of the endothelial monolayer lining the blood vessel lumen in vivo. Mixed front tracking, immersed boundary and ghost cell methods are
applied. The codes are benchmarked and validated with five selected problems. We find that the erythrocyte-leukocyte interaction, leukocyte-leukocyte interaction, and vascular geometries play important roles in leukocyte margination, initial tethering and adhesion to the vascular endothelium.
In part II of the dissertation, we studied the two-dimensional microscale Richtmyer-Meshkov interfaces and discovered the self-driven vortex-accelerated vorticity deposition (VAVD) process. Opposite-signed secondary vorticity deposited by the VAVD is rolled into vortex double layers which are extremely unstable and lead to enhanced fluid mixing. The VAVD process examined and the new quantification procedure, the circulation rate of change, comprise a new vortex paradigm for examining the effect of specific initial conditions on the evolution of Richtmyer-Meshkov and Rayleigh-Taylor interfaces through intermediate times.
Note (type = degree)
Ph.D.
Note (type = bibliography)
Includes bibliographical references (p. 152-163).
Subject (ID = SUBJ1); (authority = RUETD)
Topic
Mechanical and Aerospace Engineering
Subject (ID = SUBJ2); (authority = ETD-LCSH)
Topic
Cell adhesion--Molecular aspects
Subject (ID = SUBJ3); (authority = ETD-LCSH)
Topic
Fluid dynamics--Mathematical models
Subject (ID = SUBJ4); (authority = ETD-LCSH)
Topic
Unsteady flow (Fluid dynamics)
Subject (ID = SUBJ5); (authority = ETD-LCSH)
Topic
Liquid-liquid interfaces
RelatedItem (type = host)
TitleInfo
Title
Graduate School - New Brunswick Electronic Theses and Dissertations
Identifier (type = local)
rucore19991600001
Identifier (type = hdl)
http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.17211
Identifier
ETD_619
Location
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NjNbRU
Identifier (type = doi)
doi:10.7282/T3513ZJW
Genre (authority = ExL-Esploro)
ETD doctoral
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The author owns the copyright to this work.
Copyright
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Copyright protected
Availability
Status
Open
AssociatedEntity (AUTHORITY = rulib); (ID = 1)
Name
Gaozhu Peng
Role
Copyright holder
Affiliation
Rutgers University. Graduate School - New Brunswick
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Non-exclusive ETD license
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Author Agreement License
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I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
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