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Resolving endometriosis-induced pain utilizing a low-glycemic diet

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TitleInfo (displayLabel = Citation Title); (type = uniform)
Title
Resolving endometriosis-induced pain utilizing a low-glycemic diet
Name (ID = NAME001); (type = personal)
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Witherspoon
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Courtney
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Courtney Witherspoon
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author
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Sherman
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Adria
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Advisory Committee
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Adria Sherman
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chair
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Shapses
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Susan
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Advisory Committee
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Susan Shapses
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Storch
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Judy
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Advisory Committee
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Judy Storch
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internal member
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Worobey
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John
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Advisory Committee
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John Worobey
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internal member
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Rutgers University
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degree grantor
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Graduate School - New Brunswick
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school
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Text
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theses
OriginInfo
DateCreated (qualifier = exact)
2008
DateOther (qualifier = exact); (type = degree)
2008-01
Language
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English
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electronic
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application/pdf
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text/xml
Extent
vii, 59 pages
Abstract
This single-blinded clinical study was designed to determine if a diet consisting of foods having low glycemic indices (GI), with an emphasis on reduction of simple sugars, is an effective tool for reducing symptoms of endometriosis. Chronic inflammation may be the primary activator of endometrial tissue migration and adhesion. Studies suggest that the high levels of sugar (i.e. USDA reports 150 lbs per person a year) promote chronic inflammation. Thus, it was proposed that if there was a reduction in dietary simple sugars (i.e. low glycemic index/load), there would be a concomitant reduction in the painful symptoms of endometriosis. All subjects received healthy dietary guidance according the United States Department of Agriculture (USDA) food pyramid. The experimental group was asked to eliminate all simple sugars throughout the study.
There were no statistically significant differences in the mean Endometriosis Symptom Scores (ESS) or Glycemic Indices between the control and test groups. However, the subjects (n=9) who followed through with the trial for the entire six weeks (C=Continuers), maintained higher mean compliance scores, with intermediate Glycemic Load (GL) values, and experienced a significant decrease in endometriosis induced pain as evidenced by the substantial drop in their ESS values, compared to those who dropped out of the study (n=4). This preliminary study did not show a significant difference in the mean glycemic indices (GI) between the Control vs. Test groups. However, the mean GL was significantly lower in the Continuers than in the Dropouts. Acknowledging the fragility of reproducible results due to the small sample size, the data shows that lowering the GL of the diet reduced pain in subjects with endometriosis.
Note (type = degree)
M.S.
Note (type = bibliography)
Includes bibliographical references (p. 56-59).
Subject (ID = SUBJ1); (authority = RUETD)
Topic
Nutritional Sciences
Subject (ID = SUBJ2); (authority = ETD-LCSH)
Topic
Endometriosis--Diet therapy
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Title
Graduate School - New Brunswick Electronic Theses and Dissertations
Identifier (type = local)
rucore19991600001
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http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.17237
Identifier
ETD_737
Location
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NjNbRU
Identifier (type = doi)
doi:10.7282/T3WM1DRK
Genre (authority = ExL-Esploro)
ETD graduate
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The author owns the copyright to this work.
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Open
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Name
Courtney Witherspoon
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Copyright holder
Affiliation
Rutgers University. Graduate School - New Brunswick
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Non-exclusive ETD license
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I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
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