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Energy metabolism and body composition following recovery from anorexia nervosa

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TitleInfo (displayLabel = Citation Title); (type = uniform)
Title
Energy metabolism and body composition following recovery from anorexia nervosa
Name (ID = NAME001); (type = personal)
NamePart (type = family)
Dellava
NamePart (type = given)
Jocilyn Elizabeth
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Jocilyn Elizabeth Dellava
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RoleTerm (authority = RUETD)
author
Name (ID = NAME002); (type = personal)
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Hoffman
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Daniel
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Advisory Committee
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Daniel J Hoffman
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chair
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NamePart (type = family)
Shapses
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Sue
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Advisory Committee
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Sue A Shapses
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internal member
Name (ID = NAME004); (type = personal)
NamePart (type = family)
Wilson
NamePart (type = given)
G. Terence
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Advisory Committee
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G. Terence Wilson
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internal member
Name (ID = NAME005); (type = personal)
NamePart (type = family)
Worobey
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John
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Advisory Committee
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John Worobey
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internal member
Name (ID = NAME006); (type = personal)
NamePart (type = family)
Fried
NamePart (type = given)
Susan
Affiliation
Advisory Committee
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Susan Fried
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outside member
Name (ID = NAME007); (type = personal)
NamePart (type = family)
Hallman
NamePart (type = given)
William
Affiliation
Advisory Committee
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William K Hallman
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outside member
Name (ID = NAME008); (type = corporate)
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Rutgers University
Role
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degree grantor
Name (ID = NAME009); (type = corporate)
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Graduate School - New Brunswick
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school
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Text
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theses
OriginInfo
DateCreated (qualifier = exact)
2008
DateOther (qualifier = exact); (type = degree)
2008-05
Language
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English
PhysicalDescription
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electronic
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application/pdf
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text/xml
Extent
xx, 195 pages
Abstract
Anorexia Nervosa (AN) affects millions of women however, little is known about the long-term effect of AN on body composition and metabolism in those who recover from AN. In short-term recovery from AN women have increased central adiposity, increased cortisol levels, and low resting energy expenditure compared to women without a history of an eating disorder. However, it is still unknown if these differences in body composition, cortisol, and energy metabolism persist in long-term recovery from AN.
The long-term effect of AN on of body composition, cortisol, and energy metabolism has not been examined. In general, undernutrition has been associated with an increased risk for increased cortisol levels, altered energy metabolism, and increased central adiposity. However, it is possible that there may be differences in the effects of undernutrition occurring in adolescents or adults. Therefore, the objective of this study was to determine the relationship between a history of AN, followed by at least 2 years of recovery (RAN), on body composition, cortisol levels, and energy metabolism. Using dual energy x-ray absorptiometry, fat mass and body fat distribution did not differ between RAN and control participants. Salivary cortisol samples obtained at baseline and following a mental stress test did not differ between the two groups. While there were no differences in resting energy expenditure, even when adjusted for body composition, the respiratory quotient of RAN women was significantly lower, corresponding to a higher rate of fat oxidation, compared to C women. Based on the results of this study, it may be concluded that RAN women exhibit differences in substrate metabolism, without presenting differences in body composition, cortisol levels, and resting energy expenditure. Therefore time following undernutrition has an influence on body fat distribution, cortisol, and energy metabolism. Furthermore, RAN women should not be at risk for central adiposity, differing from those who experience undernutrition early in life.
Note (type = degree)
Ph.D.
Note (type = bibliography)
Includes bibliographical references (p. 163-194).
Subject (ID = SUBJ1); (authority = RUETD)
Topic
Nutritional Sciences
Subject (ID = SUBJ2); (authority = ETD-LCSH)
Topic
Anorexia nervosa
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TitleInfo
Title
Graduate School - New Brunswick Electronic Theses and Dissertations
Identifier (type = local)
rucore19991600001
Identifier (type = hdl)
http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.17298
Identifier
ETD_810
Location
PhysicalLocation (authority = marcorg); (displayLabel = Rutgers, The State University of New Jersey)
NjNbRU
Identifier (type = doi)
doi:10.7282/T3SF2WJD
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The author owns the copyright to this work.
Copyright
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Copyright protected
Availability
Status
Open
AssociatedEntity (AUTHORITY = rulib); (ID = 1)
Name
Jocilyn Dellava
Role
Copyright holder
Affiliation
Rutgers University. Graduate School - New Brunswick
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Type
Permission or license
Detail
Non-exclusive ETD license
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License
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Author Agreement License
Detail
I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
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