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The thermal response of biological tissue subjected to short-pulsed irradiations

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TypeOfResource
Text
TitleInfo (ID = T-1)
Title
The thermal response of biological tissue subjected to short-pulsed irradiations
SubTitle
PartName
PartNumber
NonSort
Identifier (displayLabel = ); (invalid = )
ETD_1268
Identifier (type = hdl)
http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.000051761
Language (objectPart = )
LanguageTerm (authority = ISO639-2); (type = code)
eng
Genre (authority = marcgt)
theses
Subject (ID = SBJ-1); (authority = RUETD)
Topic
Mechanical and Aerospace Engineering
Subject (ID = SBJ-2); (authority = ETD-LCSH)
Topic
Tissues--Thermal properties
Subject (ID = SBJ-3); (authority = ETD-LCSH)
Topic
Tissues--Effect of radiation on
Subject (ID = SBJ-4); (authority = ETD-LCSH)
Topic
Lasers--Physiological effect
Abstract
A combined transient radiation and hyperbolic heat conduction model is developed to simulate heat transfer of biological tissue subjected to short pulsed irradiations. For modeling the ultrafast radiation heat transfer, the Transient Discrete Ordinate Method (TDOM) is developed in the two-dimensional axisymmetric cylindrical coordinates. The hyperbolic conduction model is solved by MacCormack’s scheme with error terms correction. One combination model of radiation and heat conduction is that the radiation transfer is initiated by short pulse train irradiating until millisecond time scale and heat conduction transfer is followed. The temperature always increases by the radiation transfer and the heat is dissipated to the surrounding tissue by the hyperbolic heat conduction. The typical characteristic of the hyperbolic conduction is the thermal wave propagation rather than thermal diffusion with indefinite speed. It is found that the maximum local temperatures are higher in the hyperbolic prediction than the parabolic prediction, which can be 7% higher in the modeled dermis tissue. After about 10 thermal relaxation times, thermal waves fade away and the predictions between the hyperbolic and parabolic models are closely consistent.
Other combination model is that radiation and conduction transfer always occurs together until a second time regime. The temperature prediction is compared with the experimental result provided by Dr. Kunal Mitra’s group. Generally, the hyperbolic model combined with radiative heat transfer shows very similar result with the experimental data. It also shows high temperature increment near the laser deposition area compared with the parabolic model.
Own experimental study is conducted to evaluate the hyperbolic heat conduction phenomena. The fresh chicken tissue which is conserved the room temperature is suddenly contacted the ice block. Some of the results support the hyperbolic model by the temperature suddenly dropping rather that gradual temperature change.
The high absorbing tissue can enhance the radiation energy absorption and temperature increment is higher. The temperature increment is localized in the tissue surface region in the high scattering tissue. The focused laser beam played a role of temperature amplification around the focal region. The finer grid system is employed to catch up steep change of gradient of radiation energy absorption.
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electronic resource
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xxiii, 191 p. : ill.
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application/pdf
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text/xml
Note (type = degree)
Ph.D.
Note (type = bibliography)
Includes bibliographical references (p. 184-190)
Note (type = statement of responsibility)
by Kyunghan Kim
Name (ID = NAME-1); (type = personal)
NamePart (type = family)
Kim
NamePart (type = given)
Kyunghan
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RoleTerm (authority = RULIB); (type = )
author
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Kyunghan Kim
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Guo
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Zhixiong
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chair
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Advisory Committee
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Zhixiong Guo
Name (ID = NAME-3); (type = personal)
NamePart (type = family)
Jaluria
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Yogesh
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internal member
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Advisory Committee
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Yogesh Jaluria
Name (ID = NAME-4); (type = personal)
NamePart (type = family)
Lin
NamePart (type = given)
Hao
Role
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internal member
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Advisory Committee
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Hao Lin
Name (ID = NAME-5); (type = personal)
NamePart (type = family)
Mitra
NamePart (type = given)
Kunal
Role
RoleTerm (authority = RULIB); (type = )
outside member
Affiliation
Advisory Committee
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Kunal Mitra
Name (ID = NAME-1); (type = corporate)
NamePart
Rutgers University
Role
RoleTerm (authority = RULIB); (type = )
degree grantor
Name (ID = NAME-2); (type = corporate)
NamePart
Graduate School - New Brunswick
Role
RoleTerm (authority = RULIB); (type = )
school
OriginInfo
DateCreated (point = ); (qualifier = exact)
2008
DateOther (qualifier = exact); (type = degree)
2008-10
Place
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xx
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TitleInfo
Title
Rutgers University Electronic Theses and Dissertations
Identifier (type = RULIB)
ETD
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TitleInfo
Title
Graduate School - New Brunswick Electronic Theses and Dissertations
Identifier (type = local)
rucore19991600001
Location
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NjNbRU
Identifier (type = doi)
doi:10.7282/T3CZ37BP
Genre (authority = ExL-Esploro)
ETD doctoral
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Rights

RightsDeclaration (AUTHORITY = GS); (ID = rulibRdec0006)
The author owns the copyright to this work.
Copyright
Status
Copyright protected
Notice
Note
Availability
Status
Open
Reason
Permission or license
Note
RightsHolder (ID = PRH-1); (type = personal)
Name
FamilyName
Kim
GivenName
Kyunghan
Role
Copyright holder
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Permission or license
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DateTime
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Name
Kyunghan Kim
Affiliation
Rutgers University. Graduate School - New Brunswick
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License
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Author Agreement License
Detail
I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
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