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An adaptive sensorimotor representation for reaching in the inferior parietal lobule of behaving monkeys
Descriptive
TypeOfResource
Text
TitleInfo
(ID = T-1)
Title
An adaptive sensorimotor representation for reaching in the inferior parietal lobule of behaving monkeys
Identifier
ETD_2817
Identifier
(type = hdl)
http://hdl.rutgers.edu/1782.1/rucore10002600001.ETD.000056100
Language
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(type = code)
eng
Genre
(authority = marcgt)
theses
Subject
(ID = SBJ-1);
(authority = RUETD)
Topic
Integrative Neuroscience
Subject
(ID = SBJ-2);
(authority = ETD-LCSH)
Topic
Visual perception--Testing
Subject
(ID = SBJ-3);
(authority = ETD-LCSH)
Topic
Monkeys--Physiology
Subject
(ID = SBJ-4);
(authority = ETD-LCSH)
Topic
Sensorimotor integration
Abstract
(type = abstract)
Primates use visual guidance in order to interact with their environment. For several decades, the inferior parietal lobule (IPL) has been known to contain neurons that respond to visual stimulation and motor behavior. While the neural activity during the reaching behavior has been shown in area 7a of IPL, reach related neural responses have never been tested in the dorsal prelunate area (DP) of IPL, which is adjacent to area 7a. Furthermore, neural response prior to the reaching movement has not been assessed in DP and area 7a. The first aim was to investigate the tuning properties of single neurons in DP and area 7a. The second aim was to assess the influence of eye position signal on reaching behavior. Third, the temporal evolution of sensorimotor transformation in area 7a and DP neurons was investigated by comparing neural signals throughout the reaching task. Lastly, cortical plasticity was tested using Fresnel prisms, which displaced the visual field by 12ยบ in one of four directions: contralateral, ipsilateral, upwards, or downwards. Foveal and peripheral reaching tasks and reaching under perceptually distorted conditions were used. Neurons in area 7a and DP were observed to have differential tuning properties during the planning phase and the initiation of the reach, in addition to being selective for eye position and retinal visual stimulation. The response properties of the neurons in areas 7a and DP changed as the trial progressed in time. Differential preparatory and reach responses were observed during foveal and peripheral reaching. This implies that both eye position and retinal signals modulated the reach related responses. Alterations in spatial tuning of the neurons during all phases of the task were observed upon insertion of the Fresnel prisms imply that neural plasticity occurs as the cortex swiftly adapts to the mismatch between sensory input and motor output. The spatial tuning of the neurons did not merely compensate for the eye position shift implying that signals other than eye position affect the neural response during reaching. These combined results strongly support the claim that crucial aspects of sensorimotor transformation occur in areas 7a and DP.
PhysicalDescription
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electronic resource
Extent
xv, 177 p. : ill.
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application/pdf
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text/xml
Note
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Ph.D.
Note
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Includes bibliographical references
Note
(type = vita)
Includes vita
Note
(type = statement of responsibility)
by Anushree Karnik
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Karnik
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Anushree
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1984-
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author
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Anushree Karnik
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Krekelberg
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Bart
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chair
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Advisory Committee
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Bart Krekelberg
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Siegel
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Ralph M
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internal member
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Advisory Committee
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Ralph M Siegel
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Pare
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Denis
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internal member
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Advisory Committee
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Denis Pare
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(type = family)
Abercrombie
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Elizabeth
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internal member
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Advisory Committee
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Elizabeth Abercrombie
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Gardner
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Esther
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outside member
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Advisory Committee
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Esther Gardner
Name
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NamePart
Rutgers University
Role
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degree grantor
Name
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Graduate School - Newark
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school
OriginInfo
DateCreated
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2010
DateOther
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2010-10
Place
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xx
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TitleInfo
Title
Rutgers University Electronic Theses and Dissertations
Identifier
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ETD
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TitleInfo
Title
Graduate School - Newark Electronic Theses and Dissertations
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rucore10002600001
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NjNbRU
Identifier
(type = doi)
doi:10.7282/T37W6C02
Genre
(authority = ExL-Esploro)
ETD doctoral
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Rights
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(ID = rulibRdec0006)
The author owns the copyright to this work.
Copyright
Status
Copyright protected
Availability
Status
Open
Reason
Permission or license
RightsHolder
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(type = personal)
Name
FamilyName
Karnik
GivenName
Anushree
Role
Copyright Holder
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Type
Permission or license
DateTime
2010-08-19 12:47:45
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Role
Copyright holder
Name
Anushree Karnik
Affiliation
Rutgers University. Graduate School - Newark
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Author Agreement License
Detail
I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
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ETD
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application/x-tar
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3737600
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