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New approaches for controlling biofilm formation
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Guinta, Allison Rose. New approaches for controlling biofilm formation. Retrieved from https://doi.org/doi:10.7282/T3WM1D6D

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TitleNew approaches for controlling biofilm formation
NameGuinta, Allison Rose (author); Chikindas, Michael L. (chair); Woychik, Nancy (internal member); Takhistov, Paul (outside member); Rutgers University; Graduate School - New Brunswick
Date Created2010
Other Date2010-10 (degree)
SubjectMicrobiology and Molecular Genetics, Biofilms, Anti-infective agents, Genetic regulation, Salicylic acid, Salmonella--Genetics
Extentvii, 44 p. : ill.
DescriptionThe following thesis is composed of two chapters represented by two manuscripts. The introduction chapter examines the challenges of biofilm-associated cells in the food industry and in medical applications and novel methods for biofilm prevention through altering genetic regulation. This chapter has been submitted for publication to The International Journal of Microbiology. The second chapter is research conducted during graduate studies that has been accepted for publication in Biofilms: Formation, Development, and Properties published by Nova Science Publishers, Inc. The ability of a novel salicylic acid based poly (anhydride ester) polymer (SA-PAE) to prevent biofilms in Salmonella typhimurium MAE52 was evaluated via cell enumeration studies, pH kinetics, and salicylic acid release kinetics. SA-PAE was found to prevent biofilm formation in S. typhimurium MAE52 through disruption of a bimodal nature in pH without significantly reducing cell population. Changes in genetic regulation, reflected in the disruption of the bimodal pH, resulted in biofilm prevention.
NoteM.S.
NoteIncludes bibliographical references
NoteIncludes vita
Noteby Allison Rose Guinta
Genretheses, ETD graduate
Persistent URLhttps://doi.org/doi:10.7282/T3WM1D6D
Languageeng
CollectionGraduate School - New Brunswick Electronic Theses and Dissertations
Organization NameRutgers, The State University of New Jersey
RightsThe author owns the copyright to this work.
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