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Novel multi-electrode probe with three dimensional spatial resolution for simultaneous recording/stimulation in long-term adaptive deep brain stimulaton

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TitleInfo
Title
Novel multi-electrode probe with three dimensional spatial resolution for simultaneous recording/stimulation in long-term adaptive deep brain stimulaton
Name (type = personal)
NamePart (type = family)
Elkholy
NamePart (type = given)
Ryan M.
NamePart (type = date)
1985-
DisplayForm
Ryan Elkholy
Role
RoleTerm (authority = RULIB)
author
Name (type = personal)
NamePart (type = family)
Micheli-Tzanakou
NamePart (type = given)
Evangelia
DisplayForm
Evangelia Micheli-Tzanakou
Affiliation
Advisory Committee
Role
RoleTerm (authority = RULIB)
chair
Name (type = personal)
NamePart (type = family)
Gajic
NamePart (type = given)
Zoran
DisplayForm
Zoran Gajic
Affiliation
Advisory Committee
Role
RoleTerm (authority = RULIB)
internal member
Name (type = personal)
NamePart (type = family)
Caggiano
NamePart (type = given)
Michael
DisplayForm
Michael Caggiano
Affiliation
Advisory Committee
Role
RoleTerm (authority = RULIB)
internal member
Name (type = personal)
NamePart (type = family)
Gajic
NamePart (type = given)
Verica
DisplayForm
Verica Gajic
Affiliation
Advisory Committee
Role
RoleTerm (authority = RULIB)
outside member
Name (type = corporate)
NamePart
Rutgers University
Role
RoleTerm (authority = RULIB)
degree grantor
Name (type = corporate)
NamePart
Graduate School - New Brunswick
Role
RoleTerm (authority = RULIB)
school
TypeOfResource
Text
Genre (authority = marcgt)
theses
OriginInfo
DateCreated (qualifier = exact)
2011
DateOther (qualifier = exact); (type = degree)
2011-05
Place
PlaceTerm (type = code)
xx
Language
LanguageTerm (authority = ISO639-2b); (type = code)
eng
Subject (authority = RUETD)
Topic
Electrical and Computer Engineering
Subject (authority = ETD-LCSH)
Topic
Brain stimulation
Subject (authority = ETD-LCSH)
Topic
Probes (Electronic instruments)
RelatedItem (type = host)
TitleInfo
Title
Rutgers University Electronic Theses and Dissertations
Identifier (type = RULIB)
ETD
Note (type = degree)
Ph.D.
Note (type = bibliography)
Includes bibliographical references
Note (type = vita)
Includes vita
Note (type = statement of responsibility)
by Ryan M. Elkholy
PhysicalDescription
Extent
xii, 193 p. : ill.
Form (authority = gmd)
electronic resource
Abstract (type = abstract)
When treating neurological disorders such as Parkinson’s Disease (PD) modern technologies experience many deficiencies and/or limitations that researchers have been working towards improving. The problems that occur with modern devices are inadequate mechanical robustness, glial scarring due to tissue damage, reduced target area localization, and inability to simultaneously record/stimulate in vivo post implantation. The research presented here resolves the issues stated above, delivering the design of a novel Multi-Electrode Probe with 3-D spatial resolution and an on-board preamplification/filtering chip capable of simultaneous recording/stimulation. The probe has been modeled in Wildfire Pro/Engineer 4.0 and Finite Element Analysis (FEA) was performed in COMSOL Multiphysics 3.4. The neural chip which consists of both analog and digital circuitry was designed with Taiwan Semiconductor’s (TSMC) 0.18µm CMOS technology. The very large scale integration (VLSI) design and simulation was performed in Cadence Schematic and Spectre, respectively. The aforementioned work was done in hopes of delivering a neural probe that can eventually be used in a closed loop system for Adaptive Deep Brain Stimulation treatment.
Identifier (type = hdl)
http://hdl.rutgers.edu/1782.1/rucore10001600001.ETD.000061203
RelatedItem (type = host)
TitleInfo
Title
Graduate School - New Brunswick Electronic Theses and Dissertations
Identifier (type = local)
rucore19991600001
Location
PhysicalLocation (authority = marcorg); (displayLabel = Rutgers, The State University of New Jersey)
NjNbRU
Identifier (type = doi)
doi:10.7282/T3PK0FFC
Genre (authority = ExL-Esploro)
ETD doctoral
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Rights

RightsDeclaration (ID = rulibRdec0006)
The author owns the copyright to this work.
RightsHolder (type = personal)
Name
FamilyName
Elkholy
GivenName
Ryan
Role
Copyright Holder
RightsEvent
Type
Permission or license
DateTime (encoding = w3cdtf); (qualifier = exact); (point = start)
2011-04-14 20:22:05
AssociatedEntity
Name
Ryan Elkholy
Role
Copyright holder
Affiliation
Rutgers University. Graduate School - New Brunswick
AssociatedObject
Type
License
Name
Author Agreement License
Detail
I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
RightsEvent
DateTime (encoding = w3cdtf); (qualifier = exact); (point = start)
2011-05-31
DateTime (encoding = w3cdtf); (qualifier = exact); (point = end)
2013-05-30
Type
Embargo
Detail
Access to this PDF has been restricted at the author's request. It will be publicly available after May 30th, 2013.
Copyright
Status
Copyright protected
Availability
Status
Open
Reason
Permission or license
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2273280
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