RUcore: Rutgers University Community Repository
Association analysis of candidate genes for autism and a related phenotype, non-verbal motor speech disorder
Descriptive
TitleInfo
Title
Association analysis of candidate genes for autism and a related phenotype, non-verbal motor speech disorder
Name
(type = personal)
NamePart
(type = family)
Zimmerman
NamePart
(type = given)
Raymond A.
NamePart
(type = date)
1980-
DisplayForm
Raymond Zimmerman
Role
RoleTerm
(authority = RULIB)
author
Name
(type = personal)
NamePart
(type = family)
Brzustowicz
NamePart
(type = given)
Linda
DisplayForm
Linda Brzustowicz
Affiliation
Advisory Committee
Role
RoleTerm
(authority = RULIB)
chair
Name
(type = personal)
NamePart
(type = family)
Millonig
NamePart
(type = given)
James
DisplayForm
James Millonig
Affiliation
Advisory Committee
Role
RoleTerm
(authority = RULIB)
internal member
Name
(type = personal)
NamePart
(type = family)
Matise
NamePart
(type = given)
Tara
DisplayForm
Tara Matise
Affiliation
Advisory Committee
Role
RoleTerm
(authority = RULIB)
internal member
Name
(type = corporate)
NamePart
Rutgers University
Role
RoleTerm
(authority = RULIB)
degree grantor
Name
(type = corporate)
NamePart
Graduate School - New Brunswick
Role
RoleTerm
(authority = RULIB)
school
TypeOfResource
Text
Genre
(authority = marcgt)
theses
OriginInfo
DateCreated
(qualifier = exact)
2012
DateOther
(qualifier = exact);
(type = degree)
2012-05
CopyrightDate
(qualifier = exact)
2012
Place
PlaceTerm
(type = code)
xx
Language
LanguageTerm
(authority = ISO639-2b);
(type = code)
eng
Subject
(authority = RUETD)
Topic
Microbiology and Molecular Genetics
Subject
(authority = ETD-LCSH)
Topic
Genetic markers
Subject
(authority = ETD-LCSH)
Topic
Autism spectrum disorders
Subject
(authority = ETD-LCSH)
Topic
Mutism
Subject
(authority = ETD-LCSH)
Topic
Mute persons
RelatedItem
(type = host)
TitleInfo
Title
Rutgers University Electronic Theses and Dissertations
Identifier
(type = RULIB)
ETD
Identifier
ETD_3872
PhysicalDescription
Form
(authority = gmd)
electronic resource
InternetMediaType
application/pdf
InternetMediaType
text/xml
Extent
vi, 50 p. : ill.
Note
(type = degree)
M.S.
Note
(type = bibliography)
Includes bibliographical references
Note
(type = statement of responsibility)
by Raymond A. Zimmerman
Abstract
(type = abstract)
Using a bead-based oligonucleotide ligation SNP genotyping assay, 102 Single Nucleotide Polymorphisms (SNPs) were analyzed in a subset of Autism Genetic Resource Exchange (AGRE) families, looking at autism and a related phenotype, Non-Verbal Motor Speech Disorder (NVMSD). The NVMSD phenotype was defined using three variables from the Autism Diagnostic Interview – Revised (ADI-R), and subjects were chosen regardless of a diagnosis of autism. Genome-wide statistical analysis based on Affymetrix 5.0 SNP data revealed two large linkage regions on chromosomes 1 and 17 in the AGRE data set. Genes of interest were then identified using a software package (Ingenuity Pathway Analysis - IPA) that provides information on gene function and associated diseases. 102 SNPs in four of the genes of interest were genotyped in the AGRE families and statistically analyzed using the KELVIN software package.
Identifier
(type = hdl)
http://hdl.rutgers.edu/1782.1/rucore10001600001.ETD.000065310
RelatedItem
(type = host)
TitleInfo
Title
Graduate School - New Brunswick Electronic Theses and Dissertations
Identifier
(type = local)
rucore19991600001
Location
PhysicalLocation
(authority = marcorg);
(displayLabel = Rutgers, The State University of New Jersey)
NjNbRU
Identifier
(type = doi)
doi:10.7282/T36D5RX6
Genre
(authority = ExL-Esploro)
ETD graduate
Back to the top
Rights
RightsDeclaration
(ID = rulibRdec0006)
The author owns the copyright to this work.
RightsHolder
(type = personal)
Name
FamilyName
Zimmerman
GivenName
Raymond
Role
Copyright Holder
RightsEvent
Type
Permission or license
DateTime
(encoding = w3cdtf);
(qualifier = exact);
(point = start)
2012-04-06 19:02:04
AssociatedEntity
Name
Raymond Zimmerman
Role
Copyright holder
Affiliation
Rutgers University. Graduate School - New Brunswick
AssociatedObject
Type
License
Name
Author Agreement License
Detail
I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
Copyright
Status
Copyright protected
Availability
Status
Open
Reason
Permission or license
Back to the top
Technical
FileSize
(UNIT = bytes)
986624
OperatingSystem
(VERSION = 5.1)
windows xp
ContentModel
ETD
MimeType
(TYPE = file)
application/pdf
MimeType
(TYPE = container)
application/x-tar
FileSize
(UNIT = bytes)
993280
Checksum
(METHOD = SHA1)
797a2d2ed9f57e89e445a23669b1ef8a17b07185
Back to the top
Statistical Profile