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Quantification and comparison of quorum sensing response to various quinolone molecules in Pseudomonas aeruginosa and Burkholderia thailandensis
Descriptive
TitleInfo
Title
Quantification and comparison of quorum sensing response to various quinolone molecules in Pseudomonas aeruginosa and Burkholderia thailandensis
Name
(type = personal)
NamePart
(type = family)
Arslan
NamePart
(type = given)
Evrim
NamePart
(type = date)
1984-
DisplayForm
EVRIM ARSLAN
Role
RoleTerm
(authority = RULIB)
author
Name
(type = personal)
NamePart
(type = family)
Sheridan
NamePart
(type = given)
John B.
DisplayForm
John B. Sheridan
Affiliation
Advisory Committee
Role
RoleTerm
(authority = RULIB)
chair
Name
(type = personal)
NamePart
(type = family)
Hansen
NamePart
(type = given)
Darren B.
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Darren B. Hansen
Affiliation
Advisory Committee
Role
RoleTerm
(authority = RULIB)
internal member
Name
(type = personal)
NamePart
(type = family)
Huskey
NamePart
(type = given)
Phillip
DisplayForm
Phillip Huskey
Affiliation
Advisory Committee
Role
RoleTerm
(authority = RULIB)
internal member
Name
(type = personal)
NamePart
(type = family)
Lalancette
NamePart
(type = given)
Roger A.
DisplayForm
Roger A. Lalancette
Affiliation
Advisory Committee
Role
RoleTerm
(authority = RULIB)
internal member
Name
(type = personal)
NamePart
(type = family)
Schlegel
NamePart
(type = given)
James
DisplayForm
James Schlegel
Affiliation
Advisory Committee
Role
RoleTerm
(authority = RULIB)
internal member
Name
(type = corporate)
NamePart
Rutgers University
Role
RoleTerm
(authority = RULIB)
degree grantor
Name
(type = corporate)
NamePart
Graduate School - Newark
Role
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(authority = RULIB)
school
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Text
Genre
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theses
OriginInfo
DateCreated
(qualifier = exact)
2012
DateOther
(qualifier = exact);
(type = degree)
2012-10
CopyrightDate
(qualifier = exact)
2012
Place
PlaceTerm
(type = code)
xx
Language
LanguageTerm
(authority = ISO639-2b);
(type = code)
eng
Abstract
(type = abstract)
Bacteria have a quorum sensing mechanism that helps them communicate to other bacteria. It helps optimize activities such as altering behavior in response to other bacteria, facilitating cell-to-cell communication, and defeating competitors. By studying different quorum sensing signaling molecules in Pseudomonas aeruginosa and Burkholderia thailandensis, we have concluded that bacteria exert synergistic and antagonistic relationship in response to their environment. Bioluminescence studies have proven that different quinolones possess different characteristics. The difference in quorum sensing response between the Pseudomonas and Burkholderia species is largely dictated by the methylation of the quinolone ring named 4-hydroxy-3-methyl-2-alkylquinolines (HMAQs) rather than unsaturation of the alkyl chain of Burkholderia species. Also, our results indicate that there is little cross-talk between the quinolone quorum sensing molecules of both P. aeruginosa and methylated Burkholderia species. Furthermore, limited response to N-oxide quinolones indicates an attenuation of the quinolone quorum sensing response.
Subject
(authority = RUETD)
Topic
Chemistry
RelatedItem
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TitleInfo
Title
Rutgers University Electronic Theses and Dissertations
Identifier
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ETD
Identifier
ETD_4285
PhysicalDescription
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electronic resource
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application/pdf
InternetMediaType
text/xml
Extent
vi, 27 p. : ill.
Note
(type = degree)
M.S.
Note
(type = bibliography)
Includes bibliographical references
Note
(type = vita)
Includes vita
Note
(type = statement of responsibility)
by Evrim Arslan
Subject
(authority = ETD-LCSH)
Topic
Pseudomonas aeruginosa
Subject
(authority = ETD-LCSH)
Topic
Bacteriology
Subject
(authority = ETD-LCSH)
Topic
Quorum sensing (Microbiology)
Subject
(authority = ETD-LCSH)
Topic
Bacterial genetics
Identifier
(type = hdl)
http://hdl.rutgers.edu/1782.1/rucore10002600001.ETD.000066534
RelatedItem
(type = host)
TitleInfo
Title
Graduate School - Newark Electronic Theses and Dissertations
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rucore10002600001
Location
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(displayLabel = Rutgers, The State University of New Jersey)
NjNbRU
Identifier
(type = doi)
doi:10.7282/T3GH9GQ7
Genre
(authority = ExL-Esploro)
ETD graduate
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Rights
RightsDeclaration
(ID = rulibRdec0006)
The author owns the copyright to this work.
RightsHolder
(type = personal)
Name
FamilyName
ARSLAN
GivenName
EVRIM
Role
Copyright Holder
RightsEvent
Type
Permission or license
DateTime
(encoding = w3cdtf);
(qualifier = exact);
(point = start)
2012-09-25 17:03:16
AssociatedEntity
Name
EVRIM ARSLAN
Role
Copyright holder
Affiliation
Rutgers University. Graduate School - Newark
AssociatedObject
Type
License
Name
Author Agreement License
Detail
I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
Copyright
Status
Copyright protected
Availability
Status
Open
Reason
Permission or license
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Technical
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1354240
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windows xp
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application/pdf
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1361920
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