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Transforming academic knowledge for drug innovation
Descriptive
TitleInfo
Title
Transforming academic knowledge for drug innovation
SubTitle
a practice-based view of objects, entrepreneurs, and institutions
Name
(type = personal)
NamePart
(type = family)
Su
NamePart
(type = given)
Yun
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Yun Su
Role
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(authority = RULIB)
author
NamePart
(type = date)
1979-
Name
(type = personal)
NamePart
(type = family)
Dougherty
NamePart
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Deborah J.
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Deborah J. Dougherty
Affiliation
Advisory Committee
Role
RoleTerm
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chair
Name
(type = personal)
NamePart
(type = family)
Gittelman
NamePart
(type = given)
Michelle
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Michelle Gittelman
Affiliation
Advisory Committee
Role
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(authority = RULIB)
internal member
Name
(type = personal)
NamePart
(type = family)
Osorio
NamePart
(type = given)
Arturo
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Arturo Osorio
Affiliation
Advisory Committee
Role
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(authority = RULIB)
internal member
Name
(type = personal)
NamePart
(type = family)
Clarke
NamePart
(type = given)
Lee
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Lee Clarke
Affiliation
Advisory Committee
Role
RoleTerm
(authority = RULIB)
outside member
Name
(type = corporate)
NamePart
Rutgers University
Role
RoleTerm
(authority = RULIB)
degree grantor
Name
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NamePart
Graduate School - Newark
Role
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(authority = RULIB)
school
TypeOfResource
Text
Genre
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theses
OriginInfo
DateCreated
(qualifier = exact)
2013
DateOther
(qualifier = exact);
(type = degree)
2013-05
Place
PlaceTerm
(type = code)
xx
Language
LanguageTerm
(authority = ISO639-2b);
(type = code)
eng
Abstract
(type = abstract)
Academic-industry partnerships in biopharmaceuticals have been commonly arranged through firms licensing academic patents and universities receiving research grants and royalties. However, this arrangement does not accommodate the complexity in science. The research question of this dissertation is what kinds of social arrangements transform academic knowledge for complex innovation. I conducted interviews and field observations with scientists involved in drug discovery research. I developed a grounded theory on three dimensions of knowledge that characterize the boundaries for science-based complex innovation. One dimension is the materiality of complex knowledge, which emphasizes on the situated and contextualized learning about how drugs work in the realities of human biology. Another is the epistemic dimension, which highlights the ever-emergent nature of knowledge that motivates scientists to keep asking questions and drawing on rich scientific theories. The third is the activity dimension that directs a purpose of multidisciplinary collaboration among scientists. These dimensions reveal how scientists in the basic and clinical research communities go about creating and commercializing research for innovation. I further examined how the current academic-industry arrangements bridge the two forms of boundaries, and concluded that social arrangements have to support scientists participating in situated learning, raising questions, and engaging in activities to iteratively validate emergent findings. The contribution of this dissertation is threefold. My theory develops a deeper understanding of the content and substance of knowledge for biopharmaceutical innovation. My in-depth examination of how academic discoveries mediate practices among scientists suggests that these dimensions can create a common ground for scientists, business managers, and investors to collaborate. I also suggest the kinds of knowledge transformation that academic-industry partnerships need to accommodate to promote more effective collaboration.
Subject
(authority = RUETD)
Topic
Management
Subject
(authority = ETD-LCSH)
Topic
Pharmaceutical biotechnology industry
Subject
(authority = ETD-LCSH)
Topic
Universities and colleges--Research
Subject
(authority = ETD-LCSH)
Topic
Knowledge economy
Subject
(authority = ETD-LCSH)
Topic
Knowledge management
RelatedItem
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TitleInfo
Title
Rutgers University Electronic Theses and Dissertations
Identifier
(type = RULIB)
ETD
Identifier
ETD_4775
PhysicalDescription
Form
(authority = gmd)
electronic resource
InternetMediaType
application/pdf
InternetMediaType
text/xml
Extent
vi, 214 p. : ill.
Note
(type = degree)
Ph.D.
Note
(type = bibliography)
Includes bibliographical references
Note
(type = vita)
Includes vita
Note
(type = statement of responsibility)
by Yun Su
Subject
(authority = ETD-LCSH)
Topic
Drugs
Identifier
(type = hdl)
http://hdl.rutgers.edu/1782.1/rucore10002600001.ETD.000068785
RelatedItem
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TitleInfo
Title
Graduate School - Newark Electronic Theses and Dissertations
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rucore10002600001
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NjNbRU
Identifier
(type = doi)
doi:10.7282/T30000P2
Genre
(authority = ExL-Esploro)
ETD doctoral
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Rights
RightsDeclaration
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The author owns the copyright to this work.
RightsHolder
(type = personal)
Name
FamilyName
Su
GivenName
Yun
Role
Copyright Holder
RightsEvent
Type
Permission or license
DateTime
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(qualifier = exact);
(point = start)
2013-04-30 13:45:07
AssociatedEntity
Name
Yun Su
Role
Copyright holder
Affiliation
Rutgers University. Graduate School - Newark
AssociatedObject
Type
License
Name
Author Agreement License
Detail
I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
Copyright
Status
Copyright protected
Availability
Status
Open
Reason
Permission or license
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Technical
RULTechMD
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ETD
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windows xp
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