RUcore: Rutgers University Community Repository
From body to root
Descriptive
TitleInfo
Title
From body to root
SubTitle
alternative fabrication techniques and attachment mechanics for a tissue engineered meniscus construct
Name
(type = personal)
NamePart
(type = family)
Bundens
NamePart
(type = given)
Grace Dorothy
NamePart
(type = date)
2013-
DisplayForm
Grace Bundens
Role
RoleTerm
(authority = RULIB)
author
Name
(type = personal)
NamePart
(type = family)
Dunn
NamePart
(type = given)
Michael G
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Michael G Dunn
Affiliation
Advisory Committee
Role
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chair
Name
(type = personal)
NamePart
(type = family)
Gatt
NamePart
(type = given)
Charles J
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Charles J Gatt
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Advisory Committee
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internal member
Name
(type = personal)
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(type = family)
Freeman
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(type = given)
Joseph W
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Joseph W Freeman
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Advisory Committee
Role
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internal member
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Rutgers University
Role
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degree grantor
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Graduate School - New Brunswick
Role
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school
TypeOfResource
Text
Genre
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theses
OriginInfo
DateCreated
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2013
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(type = degree)
2013-10
Place
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xx
Language
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(authority = ISO639-2b);
(type = code)
eng
Abstract
(type = abstract)
Meniscal tears increase joint cartilage strains and contribute to the development of osteoarthritis of the knee. Tears within the meniscal body and at the root result in altered load transmission and cartilage damage, elucidating the need for tissue-engineered solutions. The first part of this study aims to examine the effect of meniscal scaffold fabrication techniques on the mechanical properties of poly (DT DDD) fibers. Electrospinning will also be evaluated as a new fabrication technique for partial meniscus replacements, preserving more native tissue than previous tissue-engineered solutions. Finally, the ovine meniscal root will be characterized in order to strengthen large animal model trials. While the human meniscus has been well characterized, little is known about the ovine meniscus, a model commonly used in orthopaedic research. Implants are more likely to fail during pre-clinical testing when their fixation technique does not take the model’s native biomechanics into account. Increased knowledge of scaffold fabrication techniques and the ovine meniscus will allow for better adaptation of tissue-engineered replacements to a large animal model, a crucial step prior to human clinical trials.
Subject
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Topic
Biomedical Engineering
RelatedItem
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TitleInfo
Title
Rutgers University Electronic Theses and Dissertations
Identifier
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ETD
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ETD_5137
PhysicalDescription
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electronic resource
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application/pdf
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text/xml
Extent
xii, 56 p. : ill.
Note
(type = degree)
M.S.
Note
(type = bibliography)
Includes bibliographical references
Note
(type = statement of responsibility)
by Grace Dorothy Bundens
Subject
(authority = ETD-LCSH)
Topic
Meniscus (Anatomy)
Subject
(authority = ETD-LCSH)
Topic
Knee--Wounds and injuries
Subject
(authority = ETD-LCSH)
Topic
Tissue engineering
RelatedItem
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TitleInfo
Title
Graduate School - New Brunswick Electronic Theses and Dissertations
Identifier
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rucore19991600001
Location
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(displayLabel = Rutgers, The State University of New Jersey)
NjNbRU
Identifier
(type = doi)
doi:10.7282/T3DN433G
Genre
(authority = ExL-Esploro)
ETD graduate
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Rights
RightsDeclaration
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The author owns the copyright to this work.
RightsHolder
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Name
FamilyName
Bundens
GivenName
Grace
Role
Copyright Holder
RightsEvent
Type
Permission or license
DateTime
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(point = start)
2013-10-02 18:59:25
AssociatedEntity
Name
Grace Bundens
Role
Copyright holder
Affiliation
Rutgers University. Graduate School - New Brunswick
AssociatedObject
Type
License
Name
Author Agreement License
Detail
I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
Copyright
Status
Copyright protected
Availability
Status
Open
Reason
Permission or license
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Technical
RULTechMD
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ContentModel
ETD
OperatingSystem
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windows xp
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