RUcore: Rutgers University Community Repository
The spirodiepoxide
Descriptive
TitleInfo
Title
The spirodiepoxide
SubTitle
a platform for diversity and target oriented synthesis
Name
(type = personal)
NamePart
(type = family)
Sharma
NamePart
(type = given)
Rojita
DisplayForm
Rojita Sharma
Role
RoleTerm
(authority = RULIB)
author
Name
(type = personal)
NamePart
(type = family)
Williams
NamePart
(type = given)
Lawrence J
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Lawrence J Williams
Affiliation
Advisory Committee
Role
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chair
Name
(type = personal)
NamePart
(type = family)
Jones
NamePart
(type = given)
Roger A
DisplayForm
Roger A Jones
Affiliation
Advisory Committee
Role
RoleTerm
(authority = RULIB)
internal member
Name
(type = personal)
NamePart
(type = family)
Hultzsch
NamePart
(type = given)
Kai C
DisplayForm
Kai C Hultzsch
Affiliation
Advisory Committee
Role
RoleTerm
(authority = RULIB)
internal member
Name
(type = personal)
NamePart
(type = family)
Ellsworth
NamePart
(type = given)
Bruce A
DisplayForm
Bruce A Ellsworth
Affiliation
Advisory Committee
Role
RoleTerm
(authority = RULIB)
outside member
Name
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NamePart
Rutgers University
Role
RoleTerm
(authority = RULIB)
degree grantor
Name
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NamePart
Graduate School - New Brunswick
Role
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school
TypeOfResource
Text
Genre
(authority = marcgt)
theses
OriginInfo
DateCreated
(qualifier = exact)
2013
DateOther
(qualifier = exact);
(type = degree)
2013-10
Place
PlaceTerm
(type = code)
xx
Language
LanguageTerm
(authority = ISO639-2b);
(type = code)
eng
Abstract
(type = abstract)
Revealed are studies on the reactivity and mechanism of spirodiepoxides and their utilization in the synthesis of highly functionalized diverse motifs. New spirodiepoxide based methodologies have been discussed including the method for synthesis of syn substituted hydroxyketone, diendiol, diyndiol, α′-hydroxy-γ-enone, dihydrofuranone, butenolide, and δ-lactone. Two complementary and stereochemically divergent methods for the synthesis of oxetan-3-ones starting from allenes via spirodiepoxides are also presented. Spirodiepoxide based cascades have also been used in the studies towards the synthesis of pectenotoxin 4 (PTX4). An unprecedented hydrogen bond directed allene epoxidation and spontaneous opening of the spirodiepoxide by the free hydroxyl group was employed in the synthesis of the F ring of PTX4. Improved protocol for the synthesis of allene and a new method for the synthesis of bromohydroxyketone have also been disclosed.
Subject
(authority = RUETD)
Topic
Chemistry and Chemical Biology
RelatedItem
(type = host)
TitleInfo
Title
Rutgers University Electronic Theses and Dissertations
Identifier
(type = RULIB)
ETD
Identifier
ETD_4949
PhysicalDescription
Form
(authority = gmd)
electronic resource
InternetMediaType
application/pdf
InternetMediaType
text/xml
Extent
xxi, 391 p. : ill.
Note
(type = degree)
Ph.D.
Note
(type = bibliography)
Includes bibliographical references
Note
(type = statement of responsibility)
by Rojita Sharma
Subject
(authority = ETD-LCSH)
Topic
Organic compounds--Synthesis
RelatedItem
(type = host)
TitleInfo
Title
Graduate School - New Brunswick Electronic Theses and Dissertations
Identifier
(type = local)
rucore19991600001
Location
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(displayLabel = Rutgers, The State University of New Jersey)
NjNbRU
Identifier
(type = doi)
doi:10.7282/T3WQ01TK
Genre
(authority = ExL-Esploro)
ETD doctoral
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Rights
RightsDeclaration
(ID = rulibRdec0006)
The author owns the copyright to this work.
RightsHolder
(type = personal)
Name
FamilyName
Sharma
GivenName
Rojita
Role
Copyright Holder
RightsEvent
Type
Permission or license
DateTime
(encoding = w3cdtf);
(qualifier = exact);
(point = start)
2013-08-28 21:28:18
AssociatedEntity
Name
Rojita Sharma
Role
Copyright holder
Affiliation
Rutgers University. Graduate School - New Brunswick
AssociatedObject
Type
License
Name
Author Agreement License
Detail
I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
RightsEvent
DateTime
(encoding = w3cdtf);
(qualifier = exact);
(point = start)
2013-10-31
DateTime
(encoding = w3cdtf);
(qualifier = exact);
(point = end)
2015-10-31
Type
Embargo
Detail
Access to this PDF has been restricted at the author's request. It will be publicly available after October 31st, 2015.
Copyright
Status
Copyright protected
Availability
Status
Open
Reason
Permission or license
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Technical
RULTechMD
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ContentModel
ETD
OperatingSystem
(VERSION = 5.1)
windows xp
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Statistical Profile