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The impact of age and exercise on antioxidants and oxidative stress in horses.

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TitleInfo
Title
The impact of age and exercise on antioxidants and oxidative stress in horses.
Name (type = personal)
NamePart (type = family)
Smarsh
NamePart (type = given)
Danielle Nicole
DisplayForm
Danielle Smarsh
Role
RoleTerm (authority = RULIB)
author
Name (type = personal)
NamePart (type = family)
Williams
NamePart (type = given)
Carey A.
DisplayForm
Carey A. Williams
Affiliation
Advisory Committee
Role
RoleTerm (authority = RULIB)
chair
Name (type = personal)
NamePart (type = family)
Arent
NamePart (type = given)
Shawn M.
DisplayForm
Shawn M. Arent
Affiliation
Advisory Committee
Role
RoleTerm (authority = RULIB)
internal member
Name (type = personal)
NamePart (type = family)
Watford
NamePart (type = given)
Malcolm
DisplayForm
Malcolm Watford
Affiliation
Advisory Committee
Role
RoleTerm (authority = RULIB)
internal member
Name (type = personal)
NamePart (type = family)
Fugaro
NamePart (type = given)
Michael
DisplayForm
Michael Fugaro
Affiliation
Advisory Committee
Role
RoleTerm (authority = RULIB)
outside member
Name (type = personal)
NamePart (type = family)
Valberg
NamePart (type = given)
Stephanie
DisplayForm
Stephanie Valberg
Affiliation
Advisory Committee
Role
RoleTerm (authority = RULIB)
outside member
Name (type = corporate)
NamePart
Rutgers University
Role
RoleTerm (authority = RULIB)
degree grantor
Name (type = corporate)
NamePart
Graduate School - New Brunswick
Role
RoleTerm (authority = RULIB)
school
TypeOfResource
Text
Genre (authority = marcgt)
theses
OriginInfo
DateCreated (qualifier = exact)
2014
DateOther (qualifier = exact); (type = degree)
2014-05
Place
PlaceTerm (type = code)
xx
Language
LanguageTerm (authority = ISO639-2b); (type = code)
eng
Abstract (type = abstract)
The present study examined the effect of acute exercise and intensive exercise training on the oxidative stress, antioxidant status, and muscle metabolism of yearlings and mature mares. Objective one was to look at the effect of repeated biopsies on muscle inflammation and oxidative stress. The pattern of biopsies does impact oxidative stress occurrence, with an alternating corner pattern resulting in less oxidative stress than biopsies taken in a row. Objective two was to look at levels of oxidative stress and antioxidants in the blood and skeletal muscle of horses after an acute bout of exercise. It was found that some markers were affected by acute exercise, but overall the test was not sufficient to induce severe oxidative stress, thus the intensity of acute exercise does impacts the level of oxidative stress endured by the horse. Objective three was to compare the effects of exercise training on oxidative stress and antioxidant status between yearlings and mares. It was found that training did significantly improve antioxidant status and reduce oxidative stress in the trained mares, while the trained yearlings did not have as significant changes in either regard. Objective four was to compare the effects of acute exercise before and after exercise training on oxidative stress, antioxidants, cortisol, and creatine kinase in two yearlings and mares. When challenged to acute exercise before training the mares had significantly higher levels of oxidative stress and cortisol and lower antioxidant status as compared to the yearlings. After exercise training, trained mature mares had lower levels of oxidative stress compared to prior training, and when challenged to acute exercise had lower oxidative stress and cortisol. The yearlings had few significant changes in oxidative stress after training and in response to acute exercise. In conclusion, young, maturing horses had lower levels of oxidative stress and cortisol, and higher levels of antioxidants, as compared to mature mares. Training can help reduce levels of oxidative stress in mature mares, while in young horses training is not as influential in reducing oxidative stress, suggesting that their young age is the most important defense against exercise-induced oxidative stress.
Subject (authority = RUETD)
Topic
Animal Sciences
Subject (authority = ETD-LCSH)
Topic
Horses--Exercise
Subject (authority = ETD-LCSH)
Topic
Oxidative stress
Subject (authority = ETD-LCSH)
Topic
Antioxidants
RelatedItem (type = host)
TitleInfo
Title
Rutgers University Electronic Theses and Dissertations
Identifier (type = RULIB)
ETD
RelatedItem (type = host)
TitleInfo
Title
Graduate School - New Brunswick Electronic Theses and Dissertations
Identifier (type = local)
rucore19991600001
Identifier
ETD_5346
Identifier (type = doi)
doi:10.7282/T35D8Q5R
PhysicalDescription
Form (authority = gmd)
electronic resource
InternetMediaType
application/pdf
InternetMediaType
text/xml
Extent
xxii, 176 p. : ill.
Note (type = degree)
Ph.D.
Note (type = bibliography)
Includes bibliographical references
Location
PhysicalLocation (authority = marcorg); (displayLabel = Rutgers, The State University of New Jersey)
NjNbRU
Note (type = statement of responsibility)
by Danielle Nicole Smarsh
Genre (authority = ExL-Esploro)
ETD doctoral
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Rights

RightsDeclaration (ID = rulibRdec0006)
The author owns the copyright to this work.
RightsHolder (type = personal)
Name
FamilyName
Smarsh
GivenName
Danielle
Role
Copyright Holder
RightsEvent
Type
Permission or license
DateTime (encoding = w3cdtf); (qualifier = exact); (point = start)
2014-03-06 16:20:50
AssociatedEntity
Name
Danielle Smarsh
Role
Copyright holder
Affiliation
Rutgers University. Graduate School - New Brunswick
AssociatedObject
Type
License
Name
Author Agreement License
Detail
I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
Copyright
Status
Copyright protected
Availability
Status
Open
Reason
Permission or license
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RULTechMD (ID = TECHNICAL1)
ContentModel
ETD
OperatingSystem (VERSION = 5.1)
windows xp
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