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Design and characterization of the tensile properties of 3-d braid-twist ligament scaffolds

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TitleInfo
Title
Design and characterization of the tensile properties of 3-d braid-twist ligament scaffolds
Name (type = personal)
NamePart (type = family)
Rao
NamePart (type = given)
Rohit
NamePart (type = date)
1990-
DisplayForm
Rohit Rao
Role
RoleTerm (authority = RULIB)
author
Name (type = personal)
NamePart (type = family)
Freeman
NamePart (type = given)
Joseph W
DisplayForm
Joseph W Freeman
Affiliation
Advisory Committee
Role
RoleTerm (authority = RULIB)
chair
Name (type = personal)
NamePart (type = family)
Dunn
NamePart (type = given)
Michael G
DisplayForm
Michael G Dunn
Affiliation
Advisory Committee
Role
RoleTerm (authority = RULIB)
internal member
Name (type = personal)
NamePart (type = family)
Olabisi
NamePart (type = given)
Ronke
DisplayForm
Ronke Olabisi
Affiliation
Advisory Committee
Role
RoleTerm (authority = RULIB)
internal member
Name (type = corporate)
NamePart
Rutgers University
Role
RoleTerm (authority = RULIB)
degree grantor
Name (type = corporate)
NamePart
Graduate School - New Brunswick
Role
RoleTerm (authority = RULIB)
school
TypeOfResource
Text
Genre (authority = marcgt)
theses
OriginInfo
DateCreated (encoding = w3cdtf); (qualifier = exact)
2015
DateOther (qualifier = exact); (type = degree)
2015-01
CopyrightDate (encoding = w3cdtf); (qualifier = exact)
2015
Place
PlaceTerm (type = code)
xx
Language
LanguageTerm (authority = ISO639-2b); (type = code)
eng
Abstract (type = abstract)
There are roughly between 100,000 -250,000 anterior cruciate ligament (ACL) injuries that are annually diagnosed in the U.S. alone. Around 50,000 of these require surgical reconstruction and replacement of the ACL [1-2]. The current treatment of choice is the use of an autograft harvested from the patellar tendon, the hamstring tendon or quadriceps tendons. However, autologous grafts are associated with a number of drawbacks including donor site morbidity and the requirement of two surgeries to carry out the ACL replacement. Therefore, alternative techniques need to be developed for ACL reconstruction. Recently tissue engineering-based scaffolds have received wide attention as potentially viable alternatives to autografts. This report discusses the development and characterization of the tensile properties of a 3-D braid twist scaffold fabricated using an automated braiding machine. The braiding angle of the scaffolds was altered in a controllable manner. Scaffolds with three different braiding angles; 53°, 63° and 72° were obtained to determine the effect of braiding angle on the tensile properties of the braid-twist scaffolds. Based on these studies scaffolds with a braiding angle of 72° were determined to have tensile characteristics most suitable for ligament replacement. Future studies will further evaluate the mechanical and biological properties of these scaffolds.
Subject (authority = RUETD)
Topic
Biomedical Engineering
Subject (authority = ETD-LCSH)
Topic
Tissue engineering
Subject (authority = ETD-LCSH)
Topic
Joints--Regeneration
Subject (authority = ETD-LCSH)
Topic
Anterior cruciate ligament
RelatedItem (type = host)
TitleInfo
Title
Rutgers University Electronic Theses and Dissertations
Identifier (type = RULIB)
ETD
Identifier
ETD_6171
PhysicalDescription
Form (authority = gmd)
electronic resource
InternetMediaType
application/pdf
InternetMediaType
text/xml
Extent
1 online resource (vi, 30 p. : ill.)
Note (type = degree)
M.S.
Note (type = bibliography)
Includes bibliographical references
Note (type = statement of responsibility)
by Rohit Rao
RelatedItem (type = host)
TitleInfo
Title
Graduate School - New Brunswick Electronic Theses and Dissertations
Identifier (type = local)
rucore19991600001
Location
PhysicalLocation (authority = marcorg); (displayLabel = Rutgers, The State University of New Jersey)
NjNbRU
Identifier (type = doi)
doi:10.7282/T3MS3VGC
Genre (authority = ExL-Esploro)
ETD graduate
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Rights

RightsDeclaration (ID = rulibRdec0006)
The author owns the copyright to this work.
RightsHolder (type = personal)
Name
FamilyName
Rao
GivenName
Rohit
Role
Copyright Holder
RightsEvent
Type
Permission or license
DateTime (encoding = w3cdtf); (qualifier = exact); (point = start)
2015-01-06 15:07:34
AssociatedEntity
Name
ROHIT RAO
Role
Copyright holder
Affiliation
Rutgers University. Graduate School - New Brunswick
AssociatedObject
Type
License
Name
Author Agreement License
Detail
I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
Copyright
Status
Copyright protected
Availability
Status
Open
Reason
Permission or license
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Technical

RULTechMD (ID = TECHNICAL1)
ContentModel
ETD
OperatingSystem (VERSION = 5.1)
windows xp
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