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Modular co-culture engineering, a new approach for metabolic engineering

Descriptive

TypeOfResource
Text
TitleInfo
Title
Modular co-culture engineering, a new approach for metabolic engineering
Name (type = personal)
NamePart (type = family)
Zhang
NamePart (type = given)
Haoran
Affiliation
Chemical & Biochemical Engineering, Rutgers University
Role
RoleTerm (authority = marcrt); (type = text)
author
Name (type = personal)
NamePart (type = family)
Wang
NamePart (type = given)
Xiaonan
Affiliation
Chemical & Biochemical Engineering, Rutgers University
Role
RoleTerm (authority = marcrt); (type = text)
author
Name (authority = RutgersOrg-Department); (type = corporate)
NamePart
Chemical & Biochemical Engineering
Name (authority = RutgersOrg-School); (type = corporate)
NamePart
School of Engineering
Genre (authority = RULIB-FS)
Article, Refereed
Genre (authority = NISO JAV)
Accepted Manuscript (AM)
Genre (authority = ExL-Esploro)
Accepted Manuscript
OriginInfo
DateIssued (encoding = w3cdtf); (keyDate = yes); (qualifier = exact)
2016
Language
LanguageTerm (authority = ISO 639-3:2007); (type = text)
English
PhysicalDescription
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application/pdf
Extent
30 p.
Extension
DescriptiveEvent
Type
Citation
DateTime (encoding = w3cdtf)
2016
AssociatedObject
Type
Journal
Relationship
Has part
Name
Metabolic engineering
Identifier (type = volume and issue)
37
Reference (type = url)
https://dx.doi.org/10.1016/j.ymben.2016.05.007
Detail
114-121
Subject (authority = local)
Topic
Modular co-culture engineering
Subject (authority = local)
Topic
Microbial co-cultures
Subject (authority = local)
Topic
Pathway modularization
Subject (authority = local)
Topic
Microbial biosynthesis
Subject (authority = LCSH)
Topic
Microbiology--Cultures and culture media
Subject (authority = LCSH)
Topic
Modularity (Engineering)
Abstract (type = abstract)
With the development of metabolic engineering, employment of a selected microbial host for accommodation of a designed biosynthetic pathway to produce a target compound has achieved tremendous success in the past several decades. Yet, increasing requirements for sophisticated microbial biosynthesis call for establishment and application of more advanced metabolic engineering methodologies. Recently, important progress has been made towards employing more than one engineered microbial strains to constitute synthetic co-cultures and modularizing the biosynthetic labor between the co-culture members in order to improve bioproduction performance. This emerging approach, referred to as modular co-culture engineering in this review, presents a valuable opportunity for expanding the scope of the broad field of metabolic engineering. We highlight representative research accomplishments using this approach, especially those utilizing metabolic engineering tools for microbial co-culture manipulation. Key benefits and major challenges associated with modular co-culture engineering are also presented and discussed.
RelatedItem (type = host)
TitleInfo
Title
Zhang, Haoran
Identifier (type = local)
rucore30193200001
RelatedItem (type = host)
TitleInfo
Title
Wang, Xiaonan
Identifier (type = local)
rucore30206300001
Location
PhysicalLocation (authority = marcorg); (displayLabel = Rutgers, The State University of New Jersey)
NjNbRU
Identifier (type = doi)
doi:10.7282/T3RB76QX
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Rights

RightsDeclaration (AUTHORITY = FS); (ID = rulibRdec0004)
Copyright for scholarly resources published in RUcore is retained by the copyright holder. By virtue of its appearance in this open access medium, you are free to use this resource, with proper attribution, in educational and other non-commercial settings. Other uses, such as reproduction or republication, may require the permission of the copyright holder.
Copyright
Status
Copyright protected
Availability
Status
Open
Reason
Permission or license
RightsEvent
Type
Permission or license
AssociatedObject
Type
License
Name
Multiple author license v. 1
Detail
I hereby grant to Rutgers, The State University of New Jersey (Rutgers) the non-exclusive right to retain, reproduce, and distribute the deposited work (Work) in whole or in part, in and from its electronic format, without fee. This agreement does not represent a transfer of copyright to Rutgers.Rutgers may make and keep more than one copy of the Work for purposes of security, backup, preservation, and access and may migrate the Work to any medium or format for the purpose of preservation and access in the future. Rutgers will not make any alteration, other than as allowed by this agreement, to the Work.I represent and warrant to Rutgers that the Work is my original work. I also represent that the Work does not, to the best of my knowledge, infringe or violate any rights of others.I further represent and warrant that I have obtained all necessary rights to permit Rutgers to reproduce and distribute the Work and that any third-party owned content is clearly identified and acknowledged within the Work.By granting this license, I acknowledge that I have read and agreed to the terms of this agreement and all related RUcore and Rutgers policies.
RightsEvent
Type
Publication notice
Detail
© 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
RightsEvent
Type
Embargo
DateTime (point = start); (encoding = w3cdtf)
2016-06-13
DateTime (point = end); (encoding = w3cdtf)
2017-09-01
Detail
Access to this PDF has been restricted due to the policy of the publisher, Elsevier, which requires a 12 month embargo from the date the article was published. The article in this repository will be publicly available after September 1, 2017.
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