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theses

The increase in the prevalence of obesity in a growing number of populations worldwide presents a rising health threat in this millennium. Overall, about 13% of the world adult population (11% of men and 15% of women) fell into the obese category in 2014.
Management of overweight and obesity used to be through non-surgical methods including diet, exercise, medication, and changing life styles. However, commitment to all these methods is very hard. Hence, surgical intervention has been used on a wide scale. Many types of bariatric surgical procedures were applied, mostly restrictive types such as Laparoscopic Sleeve Gastrectomy, Laparoscopic Adjustable Gastric Banding, or Roux-en-Y Gastric Bypass. The overall goal of this research is to identify the factors and costs associated with patients undergoing different types of gastrectomy, in terms of length of stay in the hospital and the operations’ costs in different types of clinical settings across the United States. Accordingly in the second phase of the project, a prospective study was conducted to evaluate some variables in the LSG candidates, such as hemoglobin level, vitamin levels (B12 and D), and thyroid hormone levels before and after the operation. Moreover, similar study and data sources were made use of from King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia.
Most patients who underwent the LSG had different kinds of comorbidity, for example; among 2012 candidates in the US, there were 34.22% who had hypertension, complicated or uncomplicated; 15.26% had uncomplicated diabetes; and 12.35% complained of depression.
According to this study’s results, a statistically significant association was found between length of stay in the hospitals, and consequently the total cost, and the following comorbidities: obesity (b=1.119, p<0.001), hypertension (b=0.076, p=0.022), and deficiency anemia (b=0.506, p<0.001). No statistically significant evidence of association between length of stay or total cost and hypothyroidism (p=0.12) or uncomplicated diabetes (p=0.385) was found. Regarding Saudi patients who received LSG between 2014 and 2015, no statistically significant difference between level of Hb or Vitamin B12 was found in patients before and after the LSG, while there was a statistically significant difference in the level of vitamin D before and after the operations. Although Sleeve Gastrectomy is popular currently as a solution for obesity, research into the procedure’s long-term effects is scarce. More research is required to improve outcomes and to maximize the benefits of those procedures.

ETD_7340

Ph.D.

Includes bibliographical references

by Sarah Mohammed A. Allabun

doi:10.7282/T3MG7RNS

ETD doctoral

The author owns the copyright to this work.