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Effect of insecticide diethyltoluamide (DEET) and co-applied sunscreens on percutaneous absorption
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Martos Gibaile, Nathaly Cristina. Effect of insecticide diethyltoluamide (DEET) and co-applied sunscreens on percutaneous absorption. Retrieved from https://doi.org/doi:10.7282/T38K7C7S

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TitleEffect of insecticide diethyltoluamide (DEET) and co-applied sunscreens on percutaneous absorption
NameMartos Gibaile, Nathaly Cristina (author); Michniak-Kohn, Bozena (chair); You, Guofeng (internal member); Minko, Tamara (internal member); Rutgers University; Graduate School - New Brunswick
Date Created2016
Other Date2016-05 (degree)
SubjectPharmaceutical Science, Insect baits and repellents--Health aspects, Skin absorption, Sunscreens (Cosmetics)
Extent1 online resource (xiii, 56 p. : ill.)
DescriptionThe combination of sunscreens and insect repellents is widely used by the population, in all regions of the globe. Several published papers reported that the concomitant use of oxybenzone and N,N-diethyl-m-toluamide (DEET), common actives present in such products, can enhance the percutaneous permeation of each of the actives which is an undesirable outcome. In this study, we evaluated the effects of the insecticide DEET on the permeation of sunscreens octyl methoxycinnamate and octyl salicylate. Several combinations of the UV absorbers and the insect repellent were tested and percutaneous permeation of all actives was compared when they were co-applied on human skin, in vitro. The outcomes of these studies suggest that DEET did not enhance the skin permeability of octyl salicylate and octyl methoxycinnamate. However, the UV absorbers can be potential enhancers when mixed with DEET, because when the sunscreen actives were used in combination with DEET, the resulting skin permeation of the insect repellent was higher than the control.
NoteM.S.
NoteIncludes bibliographical references
Noteby Nathaly Cristina Martos Gibaile
Genretheses, ETD graduate
Persistent URLhttps://doi.org/doi:10.7282/T38K7C7S
Languageeng
CollectionGraduate School - New Brunswick Electronic Theses and Dissertations
Organization NameRutgers, The State University of New Jersey
RightsThe author owns the copyright to this work.
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