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Polyelectrolyte complex barrier meshes for the prevention of abdominal adhesions
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Mistry, Shiv A.. Polyelectrolyte complex barrier meshes for the prevention of abdominal adhesions. Retrieved from https://doi.org/doi:10.7282/T3MS3VX6

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TitlePolyelectrolyte complex barrier meshes for the prevention of abdominal adhesions
NameMistry, Shiv A. (author); Langrana, Noshir (chair); Schloss, Rene (internal member); Berthiaume, Francois (internal member); Rutgers University; Graduate School - New Brunswick
Date Created2016
Other Date2016-05 (degree)
SubjectBiomedical Engineering, Biomedical materials, Abdomen--Surgery
Extent1 online resource (vii, 35 p. : ill.)
DescriptionAdhesions are a painful and expensive result of abdominal surgeries, specifically in the peritoneal cavity. This complication is surprisingly common and requires a second surgery, adhesiolysis, to remove it. Current solutions to adhesions either lack efficacy or produce an inflammatory response in the peritoneum. This project focuses on developing a post-surgical adhesion prevention polyelectrolyte complex (PEC) to both combat the problem of adhesions and promote an anti-inflammatory response. Initially, material properties of the PEC were investigated. Fibroblasts and macrophage cell viabilities were also studied on the PEC since both cell types play a central role in adhesion formation and inflammation. Finally, preliminary in-vivo studies were conducted to determine the true capability of the material as a post-surgical adhesion prevention method.
NoteM.S.
NoteIncludes bibliographical references
Noteby Shiv A. Mistry
Genretheses, ETD graduate
Persistent URLhttps://doi.org/doi:10.7282/T3MS3VX6
Languageeng
CollectionGraduate School - New Brunswick Electronic Theses and Dissertations
Organization NameRutgers, The State University of New Jersey
RightsThe author owns the copyright to this work.
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