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Noninvasive photoplethysmographic monitoring of pulse wave velocity and vascular stiffness for hypertension applications

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TitleInfo
Title
Noninvasive photoplethysmographic monitoring of pulse wave velocity and vascular stiffness for hypertension applications
Name (type = personal)
NamePart (type = family)
Jamkhanawala
NamePart (type = given)
Taaha
NamePart (type = date)
1991-
DisplayForm
Taaha Jamkhanawala
Role
RoleTerm (authority = RULIB)
author
Name (type = personal)
NamePart (type = family)
Li
NamePart (type = given)
John K-J
DisplayForm
John K-J Li
Affiliation
Advisory Committee
Role
RoleTerm (authority = RULIB)
chair
Name (type = personal)
NamePart (type = family)
Shoane
NamePart (type = given)
George
DisplayForm
George Shoane
Affiliation
Advisory Committee
Role
RoleTerm (authority = RULIB)
internal member
Name (type = personal)
NamePart (type = family)
Kaplan
NamePart (type = given)
Hilton
DisplayForm
Hilton Kaplan
Affiliation
Advisory Committee
Role
RoleTerm (authority = RULIB)
internal member
Name (type = corporate)
NamePart
Rutgers University
Role
RoleTerm (authority = RULIB)
degree grantor
Name (type = corporate)
NamePart
Graduate School - New Brunswick
Role
RoleTerm (authority = RULIB)
school
TypeOfResource
Text
Genre (authority = marcgt)
theses
OriginInfo
DateCreated (qualifier = exact)
2016
DateOther (qualifier = exact); (type = degree)
2016-10
CopyrightDate (encoding = w3cdtf); (qualifier = exact)
2016
Place
PlaceTerm (type = code)
xx
Language
LanguageTerm (authority = ISO639-2b); (type = code)
eng
Abstract (type = abstract)
Cardiovascular diseases are the leading cause of death globally. These usually have two main types of risk factors namely modifiable risk factors and non-modifiable risk factors. Among these, hypertension is the primary risk factor. Accurate noninvasive monitoring of hypertension in high risk patients is therefore essential in order to tackle or prevent their cardiovascular diseases. In terms of hemodynamics, increased vascular stiffness has been recognized as the main contributing factor to hypertension. This leads to the observed increase in pressure pulse propagation velocity, or pulse wave velocity, in conduit arteries. Thus, a method that can afford continuous noninvasive monitoring of vascular stiffness will be clinically desirable. To achieve this, the current investigation provides a new method of application of a photoplethysmograph (PPG) that employs light emitting diodes of visible wavelengths coupled with new ambient light detectors for optimal recording of propagating pulses. PPG sensors are placed at two different superficial arterial sites (Dual PPG) for monitoring pulse transit time (PTT) and hence pulse wave velocity (PWV) in patients. Data were simultaneously recorded in a human model, sampled by means of a Biopac System and selective filtering was applied to enhance the signal-to-noise ratio. Vascular stiffness is obtained as elastic modulus through the Moens-Korteweg formula. Interventions were imposed to observe induced changes in vascular stiffness. Results show that our current design is accurate for continuous monitoring of vascular stiffness changes. Measured pulse wave velocities agree well with clinically reported values for different arterial sites, such as ear lobe artery to radial artery and brachial artery to index finger artery. The light-weight, low cost, continuous and noninvasive PPG design can be used for future routine screening of vascular stiffness. This can be used to predict hypertension, its severity in terms of structural changes, and potential evaluation of therapeutic efficacy of anti-hypertensive drugs in hypertensives.
Subject (authority = RUETD)
Topic
Biomedical Engineering
RelatedItem (type = host)
TitleInfo
Title
Rutgers University Electronic Theses and Dissertations
Identifier (type = RULIB)
ETD
Identifier
ETD_7417
PhysicalDescription
Form (authority = gmd)
electronic resource
InternetMediaType
application/pdf
InternetMediaType
text/xml
Extent
1 online resource (x, 47 p. : ill.)
Note (type = degree)
M.S.
Note (type = bibliography)
Includes bibliographical references
Subject (authority = ETD-LCSH)
Topic
Hypertension
Note (type = statement of responsibility)
by Taaha Jamkhanawala
RelatedItem (type = host)
TitleInfo
Title
Graduate School - New Brunswick Electronic Theses and Dissertations
Identifier (type = local)
rucore19991600001
Location
PhysicalLocation (authority = marcorg); (displayLabel = Rutgers, The State University of New Jersey)
NjNbRU
Identifier (type = doi)
doi:10.7282/T390263G
Genre (authority = ExL-Esploro)
ETD graduate
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Rights

RightsDeclaration (ID = rulibRdec0006)
The author owns the copyright to this work.
RightsHolder (type = personal)
Name
FamilyName
Jamkhanawala
GivenName
Taaha
Role
Copyright Holder
RightsEvent
Type
Permission or license
DateTime (encoding = w3cdtf); (qualifier = exact); (point = start)
2016-05-31 16:11:53
AssociatedEntity
Name
Taaha Jamkhanawala
Role
Copyright holder
Affiliation
Rutgers University. Graduate School - New Brunswick
AssociatedObject
Type
License
Name
Author Agreement License
Detail
I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
Copyright
Status
Copyright protected
Availability
Status
Open
Reason
Permission or license
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Technical

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ETD
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windows xp
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2016-05-31T15:58:37
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2016-05-31T15:58:37
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