TY - JOUR TI - The role of the bed nucleus of the stria terminalis in fear and anxiety DO - https://doi.org/doi:10.7282/T36112N1 PY - 2016 AB - The bed nucleus of the stria terminalis (BNST) is a poorly understood brain structure. Most prior behavioral studies used experimental manipulations that affected the entire BNST. However recent research has made it clear that different BNST subdivisions, as well as different cell types within these divisions, serve different functions. Also, although the roles of BNST and central amygdala (CeA) in negative emotions are well established, little is known about their influence on each other. In this thesis, using in vitro whole cell patch clamp recordings, I investigated (1) how a particular peptide, called calcitonin gene related peptide (CGRP), regulates anxiety by acting on the neurons in the anterolateral BNST (BNST -AL), (2) BNST's projections to CeA, (3) the characteristics of different cell types in anteroventral BNST (BNST-AV) and their modulation by noradrenaline (NA) . KW - Neuroscience KW - Anxiety LA - eng ER -