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Evaluation of the validity of cholesterol as a biomarker for suicide in veterans
Descriptive
TitleInfo
Title
Evaluation of the validity of cholesterol as a biomarker for suicide in veterans
Name
(type = personal)
NamePart
(type = family)
Reuter
NamePart
(type = given)
Charles
NamePart
(type = date)
1977-
DisplayForm
Charles Reuter
Role
RoleTerm
(authority = RULIB)
author
Name
(type = personal)
NamePart
(type = family)
Caldwell
NamePart
(type = given)
Barbara
DisplayForm
Barbara Caldwell
Affiliation
Advisory Committee
Role
RoleTerm
(authority = RULIB)
chair
Name
(type = personal)
NamePart
(type = family)
D'Alonzo
NamePart
(type = given)
Karen
DisplayForm
Karen D'Alonzo
Affiliation
Advisory Committee
Role
RoleTerm
(authority = RULIB)
co-chair
Name
(type = corporate)
NamePart
Rutgers University
Role
RoleTerm
(authority = RULIB)
degree grantor
Name
(type = corporate)
NamePart
Graduate School - Newark
Role
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(authority = RULIB)
school
TypeOfResource
Text
Genre
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theses
OriginInfo
DateCreated
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2016
DateOther
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(type = degree)
2016-10
CopyrightDate
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2016
Place
PlaceTerm
(type = code)
xx
Language
LanguageTerm
(authority = ISO639-2b);
(type = code)
eng
Abstract
(type = abstract)
Purpose: The purpose of this study was to investigate the use of total cholesterol as a biological marker for suicidality in a veteran sample. Rationale: Previous research suggests low total cholesterol may increase the risk of suicidality in susceptible individuals by altering properties of the membranes in the brain. The low cholesterol levels appear to affect serotonin receptor exposure and cause a reduction of serotonin in the brain cells. This alters the reciprocal relationship between the serotonergic and dopaminergic systems and leads to an increase of impulsive, aggressive, self-directed aggressive behaviors, and suicidality in susceptible individuals. Methods: Records of veterans seen at the Coatesville Veterans Affairs Medical Center for suicidality between 2009 to 2015 were reviewed. The variables identified for the study were extracted and analyzed. A total of 188 veteran records were analyzed. Results: The cholesterol levels of veterans reporting suicide ideation or a suicide attempt were significantly lower than the group reporting neither [F(2, 185) = 30.19, p = .000]. There was a significant decrease in cholesterol in veterans who reported suicide ideation or a suicide attempt, when compared to an earlier visit which they were not reporting any such suicidality (t(186) = 7.61, p < 0.05). When attempting to define the characteristics of veterans who reported either suicide ideation or a suicide attempt, it was clear that one group was younger, leaner, had more anxiety, sleep problems, and education than the other group. Conclusions: There is compelling evidence that there may be a link between suicide ideation or a suicide attempt and a change in total cholesterol levels in veterans. More prospective research is needed to assess the reduction in total cholesterol levels to help clinicians identify veterans who are most at risk for suicide ideation or a suicide attempt.
Subject
(authority = RUETD)
Topic
Nursing
RelatedItem
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TitleInfo
Title
Rutgers University Electronic Theses and Dissertations
Identifier
(type = RULIB)
ETD
Identifier
ETD_7498
PhysicalDescription
Form
(authority = gmd)
electronic resource
InternetMediaType
application/pdf
InternetMediaType
text/xml
Extent
1 online resource (x, 122 p. : ill.)
Note
(type = degree)
Ph.D.
Note
(type = bibliography)
Includes bibliographical references
Subject
(authority = ETD-LCSH)
Topic
Veterans--Mental health
Subject
(authority = ETD-LCSH)
Topic
Cholesterol
Note
(type = statement of responsibility)
by Charles Reuter
RelatedItem
(type = host)
TitleInfo
Title
Graduate School - Newark Electronic Theses and Dissertations
Identifier
(type = local)
rucore10002600001
Location
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(authority = marcorg);
(displayLabel = Rutgers, The State University of New Jersey)
NjNbRU
Identifier
(type = doi)
doi:10.7282/T3M047TV
Genre
(authority = ExL-Esploro)
ETD doctoral
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Rights
RightsDeclaration
(ID = rulibRdec0006)
The author owns the copyright to this work.
RightsHolder
(type = personal)
Name
FamilyName
Reuter
GivenName
Charles
Role
Copyright Holder
RightsEvent
Type
Permission or license
DateTime
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(qualifier = exact);
(point = start)
2016-08-17 15:52:36
AssociatedEntity
Name
Charles Reuter
Role
Copyright holder
Affiliation
Rutgers University. Graduate School - Newark
AssociatedObject
Type
License
Name
Author Agreement License
Detail
I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
Copyright
Status
Copyright protected
Availability
Status
Open
Reason
Permission or license
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Technical
RULTechMD
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ETD
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windows xp
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1.4
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DateCreated
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2016-09-10T12:33:39
DateCreated
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2016-09-10T12:33:39
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