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Experimental and Mathematical Analyses Relating Circadian Period and Phase of Entrainment in Neurospora crassa

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TypeOfResource
Text
TitleInfo
Title
Experimental and Mathematical Analyses Relating Circadian Period and Phase of Entrainment in Neurospora crassa
Name (authority = orcid); (authorityURI = http://id.loc.gov/vocabulary/identifiers/orcid.html); (type = personal); (valueURI = http://orcid.org/0000-0001-8225-4220)
NamePart (type = family)
Lee
NamePart (type = given)
Kwangwon
Affiliation
Biology; Center for Computational and Integrative Biology (CCIB), Rutgers University
Role
RoleTerm (authority = marcrt); (type = text)
author
Name (type = personal)
NamePart (type = family)
Kumar
NamePart (type = given)
Prithvi Shiva
Affiliation
Biology, Rutgers University
Role
RoleTerm (authority = marcrt); (type = text)
author
Name (type = personal)
NamePart (type = family)
McQuade
NamePart (type = given)
Sean
Affiliation
Center for Computational and Integrative Biology (CCIB), Rutgers University
Role
RoleTerm (authority = marcrt); (type = text)
author
Name (type = personal)
NamePart (type = family)
Lee
NamePart (type = given)
Joshua Y.
Role
RoleTerm (authority = marcrt); (type = text)
author
Affiliation
Center for Computational and Integrative Biology (CCIB), Rutgers University
Name (type = personal)
NamePart (type = family)
Park
NamePart (type = given)
Sohyun
Affiliation
Biology, Rutgers University
Role
RoleTerm (authority = marcrt); (type = text)
author
Name (type = personal)
NamePart (type = family)
An
NamePart (type = given)
Zheming
Affiliation
Center for Computational and Integrative Biology (CCIB), Rutgers University
Role
RoleTerm (authority = marcrt); (type = text)
author
Name (type = personal)
NamePart (type = family)
Piccoli
NamePart (type = given)
Benedetto
Affiliation
Center for Computational and Integrative Biology (CCIB), Rutgers University
Role
RoleTerm (authority = marcrt); (type = text)
author
Name (authority = RutgersOrg-Department); (type = corporate)
NamePart
Biology
Name (authority = RutgersOrg-School); (type = corporate)
NamePart
Camden College of Arts and Sciences
Name (authority = RutgersOrg-Department); (type = corporate)
NamePart
Center for Computational and Integrative Biology (CCIB)
Genre (authority = RULIB-FS)
Article, Refereed
Genre (authority = NISO JAV)
Accepted Manuscript (AM)
Note (type = peerReview)
Peer reviewed
OriginInfo
DateIssued (encoding = w3cdtf); (keyDate = yes)
2017
Abstract (type = Abstract)
Circadian rhythms are observed in most organisms on earth and are known to play a major role in successful adaptation to the 24-h cycling environment. Circadian phenotypes are characterized by a free-running period that is observed in constant conditions and an entrained phase that is observed in cyclic conditions. Thus, the relationship between the free-running period and phase of entrainment is of interest. A popular simple rule has been that the entrained phase is the expression of the period in a cycling environment (i.e., that a short period causes an advanced phase and a long period causes a delayed phase). However, there are experimental data that are not explained by this simple relationship, and no systematic study has been done to explore all possible period-phase relationships. Here, we show the existence of stable period-phase relationships that are exceptions to this rule. First, we analyzed period-phase relationships using populations with different degrees of genome complexity. Second, we generated isogenic F1 populations by crossing 14 classical period mutants to the same female and analyzed 2 populations with a short period/delayed phase and a long period/advanced phase. Third, we generated a mathematical model to account for such variable relationships between period and phase. Our analyses support the view that the circadian period of an organism is not the only predictor of the entrained phase.
Language
LanguageTerm (authority = ISO 639-3:2007); (type = text)
English
PhysicalDescription
InternetMediaType
application/pdf
Extent
10 p.
Subject (authority = local)
Topic
Period
Subject (authority = local)
Topic
Phase of entrainment
Subject (authority = local)
Topic
Ecotypes
Subject (authority = local)
Topic
Mathematical model
Subject (authority = local)
Topic
Familial sleep phase syndrome
Subject (authority = local)
Topic
Thioredoxin reductase
Subject (authority = local)
Topic
ATP dependent RNA helicase
Extension
DescriptiveEvent
Type
Citation
DateTime (encoding = w3cdtf)
2017
AssociatedObject
Name
Journal of Biological Rhythms
Type
Journal
Relationship
Has part
Reference (type = url)
http://doi.org/10.1177/0748730417738611
Identifier (type = volume and issue)
32(6)
Detail
550-559
Extension
DescriptiveEvent
Type
Grant award
AssociatedEntity
Role
Funder
Name
National Institutes of Health
AssociatedEntity
Role
Originator
Name
Kwangwon Lee
AssociatedObject
Type
Grant number
Name
R15GM117523-01
RelatedItem (type = host)
TitleInfo
Title
Lee, Kwangwon
Identifier (type = local)
rucore30242200001
Location
PhysicalLocation (authority = marcorg); (displayLabel = Rutgers, The State University of New Jersey)
NjNbRU
Identifier (type = doi)
doi:10.7282/T3736TZ2
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Rights

RightsDeclaration (AUTHORITY = FS); (ID = rulibRdec0004); (TYPE = [FS] statement #1)
Copyright for scholarly resources published in RUcore is retained by the copyright holder. By virtue of its appearance in this open access medium, you are free to use this resource, with proper attribution, in educational and other non-commercial settings. Other uses, such as reproduction or republication, may require the permission of the copyright holder.
Copyright
Status
Copyright protected
Availability
Status
Open
Reason
Permission or license
RightsEvent
Type
Permission or license
AssociatedObject
Type
License
Name
Multiple author license v. 1
Detail
I hereby grant to Rutgers, The State University of New Jersey (Rutgers) the non-exclusive right to retain, reproduce, and distribute the deposited work (Work) in whole or in part, in and from its electronic format, without fee. This agreement does not represent a transfer of copyright to Rutgers. Rutgers may make and keep more than one copy of the Work for purposes of security, backup, preservation, and access and may migrate the Work to any medium or format for the purpose of preservation and access in the future. Rutgers will not make any alteration, other than as allowed by this agreement, to the Work. I represent and warrant to Rutgers that the Work is my original work. I also represent that the Work does not, to the best of my knowledge, infringe or violate any rights of others. I further represent and warrant that I have obtained all necessary rights to permit Rutgers to reproduce and distribute the Work and that any third-party owned content is clearly identified and acknowledged within the Work. By granting this license, I acknowledge that I have read and agreed to the terms of this agreement and all related RUcore and Rutgers policies.
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Technical

RULTechMD (ID = TECHNICAL1)
ContentModel
Document
CreatingApplication
Version
1.6
DateCreated (point = start); (encoding = w3cdtf); (qualifier = exact)
2017-11-29T06:08:59
DateCreated (point = start); (encoding = w3cdtf); (qualifier = exact)
2017-11-24T12:22:37
ApplicationName
Adobe PDF Library 9.9; modified using iText 4.2.0 by 1T3XT
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