Description
TitleCrystallization and dissolution studies of calcium oxalate monohydrate
Date Created2018
Other Date2018-05 (degree)
Extent1 online resource (xiii, 64 p. : ill.)
DescriptionCalcium oxalate monohydrate (COM), the most stable hydrate of calcium oxalate (CaOx) at typical room temperatures and pressures, can produce undesirable effects in certain systems, such as kidney stone disease in humans, scale deposits in mechanical equipment, and patinas on art monuments. COM dissolution has been considered as a way to remove COM crystals in such systems. However, there are only a few, if any, effective solutions that can be used in the aforementioned systems. In this study, a microfluidic approach has been used to characterize the COM dissolution abilities of various dissolution agents in the pH range of 3-9. The dissolution agents consisted of eight carboxylic acid compounds: acetic acid, formic acid, DL-malic acid, succinic acid, citric acid, hydroxycitric acid, 1, 2, 3, 4-cyclobutanetetracarboxylic acid (H4CBUT), and ethylenediaminetetraacetic acid (EDTA). COM crystals were synthesized and dissolved using two different microfluidic devices, namely a 3-input, 3-output device and a 1-input, 1-output device. Results demonstrate that EDTA, H4CBUT, citrate, and hydroxycitrate have a relatively strong ability to dissolve COM crystals in the pH range of 7 to 9. At solution pH values of 5 and 7, acetate, succinate, EDTA, H4CBUT, and citrate were significantly more effective at COM crystal dissolution than the other solution examined. Succinate, malate, and acetate seemed to have no significant benefit. Overall, the number of carboxylic acid functional groups appeared to give an indication of which dissolution agent would be most effective at dissolving COM crystals. As expected, water alone exhibited relatively poor COM dissolution capabilities at pH values greater than 5.
NoteM.S.
NoteIncludes bibliographical references
Noteby Magata Nkuba
Genretheses, ETD graduate
Languageeng
CollectionCamden Graduate School Electronic Theses and Dissertations
Organization NameRutgers, The State University of New Jersey
RightsThe author owns the copyright to this work.
Statistical Profile