Staff View
Analysis of healthcare outcomes and cost associated with cardiovascular conditions and stroke in human immunodeficiency virus (HIV) patients admitted in U.S. hospitals from 2012 to 2014

Descriptive

TitleInfo
Title
Analysis of healthcare outcomes and cost associated with cardiovascular conditions and stroke in human immunodeficiency virus (HIV) patients admitted in U.S. hospitals from 2012 to 2014
Name (type = personal)
NamePart (type = family)
Charles
NamePart (type = given)
Dréanne Laurent
NamePart (type = date)
1955-
DisplayForm
Dréanne Laurent Charles
Role
RoleTerm (authority = RULIB)
author
Name (type = personal)
NamePart (type = family)
Haque
NamePart (type = given)
Syed
DisplayForm
Syed Haque
Affiliation
Advisory Committee
Role
RoleTerm (authority = RULIB)
chair
Name (type = personal)
NamePart (type = family)
Shankar
NamePart (type = given)
Srinivasan
DisplayForm
Srinivasan Shankar
Affiliation
Advisory Committee
Role
RoleTerm (authority = RULIB)
internal member
Name (type = personal)
NamePart (type = family)
Coffman
NamePart (type = given)
Frederick
DisplayForm
Frederick Coffman
Affiliation
Advisory Committee
Role
RoleTerm (authority = RULIB)
internal member
Name (type = corporate)
NamePart
Rutgers University
Role
RoleTerm (authority = RULIB)
degree grantor
Name (type = corporate)
NamePart
School of Health Professions
Role
RoleTerm (authority = RULIB)
school
TypeOfResource
Text
Genre (authority = marcgt)
theses
OriginInfo
DateCreated (qualifier = exact)
2019
DateOther (qualifier = exact); (type = degree)
2019-01
CopyrightDate (encoding = w3cdtf)
2019
Place
PlaceTerm (type = code)
xx
Language
LanguageTerm (authority = ISO639-2b); (type = code)
eng
Abstract (type = abstract)
Objectives: To predict death, evaluate cost and hospital length of stay (LOS) associated with cardiovascular disease (CVD) and stroke in human immunodeficiency virus (HIV) patients during hospitalization.
Background: The risk for developing major CVDs and stroke in HIV individuals has been acknowledged. However, the healthcare outcomes, financial impact, and LOS linked to these diseases in hospitalized HIV individuals have not been concurrently and adequately evaluated.
Design: A retrospective observational study where hospital discharge data between 2012 and 2014 were obtained from the National Inpatient Sample (NIS). The Agency for Healthcare Research and Quality (AHRQ) comorbidity measure CM_AIDS was used to identify HIV patients with coexisting medical conditions. Furthermore, HIV patients with Acute Myocardial Infarction (AMI), Coronary Artery Disease (CAD), Congested Heart Failure (CHF), and Atrial Fibrillation (A Fib), and Stroke were selected using the appropriate International Classifications of Disease, Ninth Edition, Clinical Modification (ICD-9-CM) codes.
Method: Multivariate logistic regression and generalized linear (GLM) models were respectively used to predict death, evaluate cost and LOS.
Results: 39,540 de-identified HIV patients aged 18 to 79 years were selected for the study. From this cohort were AMI 573(1.45%), CAD 484(1.23%), CHF 1394(3.53%), and A Fib 440(1.11%), and stroke 725(1.84%). HIV patients with stroke were significantly more likely than HIV patients without stroke to die [OR = 4.721 95% CI (2.899-7.688)]. The likelihood of death for HIV patients with the remaining CVDs was observed as follows: CHF [OR = 2.610 95% CI (1.972-3.453)]; AMI [OR = 2.342 95% CI (1.576-3.480)]; A Fib [OR = 1.980 95% CI (0.783-5.002)]; and CAD [OR = 0.377 95% CI (0.140-1.014)]. HIV patients with AMI (P<.0001) incurred the highest average cost compared to HIV without AMI, followed by stroke (P<.0001), CHF (P<.0009), CAD (P<0.1456), and A Fib (P<0.3669). HIV patients with stroke (P<.0001) experienced a longer average LOS compared to HIV without stroke followed by CHF (P<.0059), CAD (P<.0328), A Fib (P<0.1032), and AMI (P<0.9401).
Conclusions: HIV patients with stroke were more likely to die and stay longer in hospital. CHF was more prevalent. AMI was costliest. Minimal disparity was observed in the analyses after adjusting for demographic and socio-economic factors. More studies are needed to confirm these results.
Subject (authority = RUETD)
Topic
Biomedical Informatics
Subject (authority = ETD-LCSH)
Topic
HIV-positive persons -- Health risk assessment
Subject (authority = ETD-LCSH)
Topic
Cerebrovascular disease
Subject (authority = ETD-LCSH)
Topic
Cardiovascular system -- Diseases
RelatedItem (type = host)
TitleInfo
Title
Rutgers University Electronic Theses and Dissertations
Identifier (type = RULIB)
ETD
Identifier
ETD_9413
PhysicalDescription
Form (authority = gmd)
electronic resource
InternetMediaType
application/pdf
InternetMediaType
text/xml
Extent
1 online resource (158 pages : illustrations)
Note (type = degree)
Ph.D.
Note (type = bibliography)
Includes bibliographical references
Note (type = statement of responsibility)
by Dréanne Laurent Charles
RelatedItem (type = host)
TitleInfo
Title
School of Health Professions ETD Collection
Identifier (type = local)
rucore10007400001
Location
PhysicalLocation (authority = marcorg); (displayLabel = Rutgers, The State University of New Jersey)
NjNbRU
Identifier (type = doi)
doi:10.7282/t3-rgax-yd55
Genre (authority = ExL-Esploro)
ETD doctoral
Back to the top

Rights

RightsDeclaration (ID = rulibRdec0006)
The author owns the copyright to this work.
RightsHolder (type = personal)
Name
FamilyName
Charles
GivenName
Dréanne
MiddleName
Laurent
Role
Copyright Holder
RightsEvent
Type
Permission or license
DateTime (encoding = w3cdtf); (qualifier = exact); (point = start)
2018-12-10 13:05:26
AssociatedEntity
Name
Dreanne Charles
Role
Copyright holder
Affiliation
Rutgers University. School of Health Professions
AssociatedObject
Type
License
Name
Author Agreement License
Detail
I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
RightsEvent
Type
Embargo
DateTime (encoding = w3cdtf); (qualifier = exact); (point = start)
2019-01-31
DateTime (encoding = w3cdtf); (qualifier = exact); (point = end)
2019-08-02
Detail
Access to this PDF has been restricted at the author's request. It will be publicly available after August 2nd, 2019.
Copyright
Status
Copyright protected
Availability
Status
Open
Reason
Permission or license
Back to the top

Technical

RULTechMD (ID = TECHNICAL1)
ContentModel
ETD
OperatingSystem (VERSION = 5.1)
windows xp
CreatingApplication
Version
1.7
DateCreated (point = end); (encoding = w3cdtf); (qualifier = exact)
2019-01-24T14:43:43
DateCreated (point = end); (encoding = w3cdtf); (qualifier = exact)
2019-01-24T14:43:43
Back to the top
Version 8.3.13
Rutgers University Libraries - Copyright ©2021