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Multidimensional hybrid nanomaterials for advanced theragnostic applications
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Descriptive

TitleInfo
Title
Multidimensional hybrid nanomaterials for advanced theragnostic applications
Name (type = personal)
NamePart (type = family)
Yang
NamePart (type = given)
Letao
NamePart (type = date)
1990-
DisplayForm
Letao Yang
Role
RoleTerm (authority = RULIB)
author
Name (type = personal)
NamePart (type = family)
Lee
NamePart (type = given)
Ki-Bum
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Ki-Bum Lee
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Advisory Committee
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chair
Name (type = personal)
NamePart (type = family)
Li
NamePart (type = given)
Jing
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Jing Li
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Advisory Committee
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internal member
Name (type = personal)
NamePart (type = family)
Garfunkel
NamePart (type = given)
Eric
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Eric Garfunkel
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Advisory Committee
Role
RoleTerm (authority = RULIB)
internal member
Name (type = personal)
NamePart (type = family)
Cai
NamePart (type = given)
Li
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Li Cai
Affiliation
Advisory Committee
Role
RoleTerm (authority = RULIB)
outside member
Name (type = corporate)
NamePart
Rutgers University
Role
RoleTerm (authority = RULIB)
degree grantor
Name (type = corporate)
NamePart
School of Graduate Studies
Role
RoleTerm (authority = RULIB)
school
TypeOfResource
Text
Genre (authority = marcgt)
theses
OriginInfo
DateCreated (qualifier = exact)
2019
DateOther (qualifier = exact); (type = degree)
2019-01
CopyrightDate (encoding = w3cdtf)
2019
Place
PlaceTerm (type = code)
xx
Language
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eng
Abstract (type = abstract)
Nanomedicine is a multidisciplinary field that develops and translate biologically functionalized nanomaterials for the treatment or diagnosis of injuries and diseases. Taking advantage of the high surface-to-volume ratio and the unique physicochemical properties of nanomaterials, nanomedicine has shown great potential for many clinical theragnostic applications. In this dissertation, to further advance nanomaterials-based medical applications, multidimensional hybrid nanomaterials were developed by addressing the critical challenges of current nanotherapeutics. For cancer treatment, 0D-2D hybrid nanomaterials were synthesized and applied for the photothermal therapy-based cancer ablation by combining the surface property of 2D nanomaterials and the optical properties of plasmonic and carbon nanomaterial. To address the slow- or non-biodegradability of 2D carbon nanomaterials, 3D nanoscaffolds assembled from MnO2-based 2D nanomaterials were designed and synthesized for stem cell therapy. By further developing a 1D-2D hybrid nanostructure, highly sensitive biosensing platform was also fabricated using graphene and gold nanoarrays. Lastly, a method to high throughput print 0D, 1D and 2D nanostructures in a single platform was developed for providing quantitative design principles of nanomaterials-based medical applications. Collectively, by showcasing the design and synthesis of multidimensional nanomaterials for theragnostic applications, this dissertation is aimed to provide useful insights for the next generation precision and personalized medicine based on hybrid nanomaterials.
Subject (authority = RUETD)
Topic
Chemistry and Chemical Biology
Subject (authority = ETD-LCSH)
Topic
Nanomedicine
RelatedItem (type = host)
TitleInfo
Title
Rutgers University Electronic Theses and Dissertations
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ETD
Identifier
ETD_9500
PhysicalDescription
Form (authority = gmd)
electronic resource
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application/pdf
InternetMediaType
text/xml
Extent
1 online resource (321 pages) : illustrations
Note (type = degree)
Ph.D.
Note (type = bibliography)
Includes bibliographical references
Note (type = statement of responsibility)
by Letao Yang
RelatedItem (type = host)
TitleInfo
Title
School of Graduate Studies Electronic Theses and Dissertations
Identifier (type = local)
rucore10001600001
Location
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NjNbRU
Identifier (type = doi)
doi:10.7282/t3-tmgr-v292
Genre (authority = ExL-Esploro)
ETD doctoral
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Rights

RightsDeclaration (ID = rulibRdec0006)
The author owns the copyright to this work.
RightsHolder (type = personal)
Name
FamilyName
Yang
GivenName
Letao
Role
Copyright Holder
RightsEvent
Type
Permission or license
DateTime (encoding = w3cdtf); (qualifier = exact); (point = start)
2019-01-07 19:20:56
AssociatedEntity
Name
Letao Yang
Role
Copyright holder
Affiliation
Rutgers University. School of Graduate Studies
AssociatedObject
Type
License
Name
Author Agreement License
Detail
I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
RightsEvent
Type
Embargo
DateTime (encoding = w3cdtf); (qualifier = exact); (point = start)
2019-01-31
DateTime (encoding = w3cdtf); (qualifier = exact); (point = end)
2021-01-30
Detail
Access to this PDF has been restricted at the author's request. It will be publicly available after January 30th, 2021.
Copyright
Status
Copyright protected
Availability
Status
Open
Reason
Permission or license
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Technical

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