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Electronic phenotyping via the anchor and learn framework with physical therapy emphasis

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TitleInfo
Title
Electronic phenotyping via the anchor and learn framework with physical therapy emphasis
Name (type = personal)
NamePart (type = family)
Volansky
NamePart (type = given)
Matthew
NamePart (type = date)
1968-
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Matthew Volansky
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author
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Srinivasan
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Shankar
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Shankar Srinivasan
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Advisory Committee
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chair
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Frederick
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Frederick Coffman
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Advisory Committee
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internal member
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Keehan
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Jane
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Jane Keehan
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Advisory Committee
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outside member
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Rutgers University
Role
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degree grantor
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School of Health Professions
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theses
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2020
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2020-01
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English
Abstract (type = abstract)
Background: When delivering evidence-based care at the bedside, learning with anchors is a proven method of efficiently learning statistically driven patient phenotypes. Such libraries currently learn with anchor terms that are universally suspect in their ability to support evidence-based practice for physical therapists (PT) within electronic medical records (EMRs).

Methods: A definition of anchor terms for venous thromboembolism (VTE) was developed using structured and unstructured retrospective data from PT documentation within two separate EMRs. The learned PT specific VTE phenotype anchor terms were compared against the published PT clinical practice guideline and clinician documentation for consistency. The learned PT specific VTE phenotype anchor terms were then evaluated against the published learned anchors derived from physician-based documentation.

Results: Two of the top 25 anchors showed a statistically significant correlation with the presence of VTE: ‘vessel’ (P <0.001) and ‘pe’ (P < 0.05). The top 20% most frequently appearing learned anchor terms in descending order of total observed frequency was ‘boot’ (12.2%), ‘movement’ (10.4%), ‘develop’ (10.1%), ‘cad’ (9.5%) and ‘pulmonary’ (9.2%).
Discussion: This research provides new insight into the relationship between anchor terms and the documentation of PT. The data indicate that the top 20% of discovered physical therapy derived phenotype terms for VTE anchors did not match the existing physician derived phenotype definition for VTE. Based on the existing physician derived anchor terms, clinical decision support tools for VTE would not have been triggered if used by the PT.

Conclusion: The delivery of patient-centered care requires an interdisciplinary team of clinicians to achieve optimal patient outcomes. Evidenced-based practice is enhanced through the presence of clinical decision support tools in the clinical workflow of the modern healthcare system. Before this research, there did not exist an established set of anchor terms with a likelihood of detecting the presence of VTE within the profession of physical therapy. An initial listing of such anchor variables has now been discovered. Further research is needed to expand the ability of machine learning classifiers to identify patients both at risk and with active disease.
Subject (authority = RUETD)
Topic
Biomedical Informatics
Subject (authority = local)
Topic
Physical therapy
Subject (authority = LCSH)
Topic
Phenotype
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Rutgers University Electronic Theses and Dissertations
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ETD_10415
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1 online resource (xii, 185 pages) : illustrations
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Ph.D.
Note (type = bibliography)
Includes bibliographical references
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School of Health Professions ETD Collection
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rucore10007400001
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Identifier (type = doi)
doi:10.7282/t3-942s-x435
Genre (authority = ExL-Esploro)
ETD doctoral
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The author owns the copyright to this work.
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Volansky
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Matthew
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Permission or license
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2019-11-12 09:42:32
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Matthew Volansky
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Rutgers University. School of Health Professions
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I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
Copyright
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Copyright protected
Availability
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Open
Reason
Permission or license
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