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Incorporating Schwann cells as a mediator of spinal cord outgrowth for regenerative therapies
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Ayers, Brian Laurence. Incorporating Schwann cells as a mediator of spinal cord outgrowth for regenerative therapies. Retrieved from https://doi.org/doi:10.7282/t3-hnkn-3a38

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TitleIncorporating Schwann cells as a mediator of spinal cord outgrowth for regenerative therapies
NameAyers, Brian Laurence (author); Vazquez, Maribel (chair); Firestein, Bonnie L (internal member); Cai, Li (internal member); Rutgers University; School of Graduate Studies
Date Created2020
Other Date2020-05 (degree)
SubjectBiomedical Engineering, Myelin sheath
Extent1 online resource (vi, 32 pages) : illustrations
DescriptionThere are millions of individuals who are affected by motor disabilities and peripheral neuropathy in the USA due to autoimmune disease, onset from infection, and chronic conditions. Peripheral neuropathy is a common effect of many diseases, and its prevalence is increasing with rising numbers of diabetic and obese individuals. The Schwann cell plays a key role in the physiology of the involved structures, and its regenerative capacities warrant its consideration and inclusion in mobility disorder and peripheral neuropathy therapies. Despite this, co-culture with spinal cord explants has previously been uninvestigated. This work establishes a model of the peripheral nervous system by co-culturing spinal cord explants with Schwann cells in extracellular solutions in vitro with the goal of advancing therapies for mobility and peripheral neuropathy disorders.
NoteM.S.
NoteIncludes bibliographical references
Genretheses, ETD graduate
Persistent URLhttps://doi.org/doi:10.7282/t3-hnkn-3a38
LanguageEnglish
CollectionSchool of Graduate Studies Electronic Theses and Dissertations
Organization NameRutgers, The State University of New Jersey
RightsThe author owns the copyright to this work.
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