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Predictive modeling and analyses of national emergency department data for improving patient outcomes of nephrolithiasis

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TitleInfo
Title
Predictive modeling and analyses of national emergency department data for improving patient outcomes of nephrolithiasis
Name (type = personal)
NamePart (type = family)
Stewart
NamePart (type = given)
Kori
NamePart (type = date)
1979
DisplayForm
Stewart, Kori, 1979-
Role
RoleTerm (authority = RULIB); (type = text)
author
Name (type = personal)
NamePart (type = family)
Srinivasan
NamePart (type = given)
Shankar
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Shankar Srinivasan
Affiliation
Advisory Committee
Role
RoleTerm (authority = RULIB)
chair
Name (type = personal)
NamePart (type = family)
Coffman
NamePart (type = given)
Fredrick
DisplayForm
Fredrick Coffman
Affiliation
Advisory Committee
Role
RoleTerm (authority = RULIB)
internal member
Name (type = personal)
NamePart (type = family)
Lynch
NamePart (type = given)
John P
DisplayForm
John P Lynch
Affiliation
Advisory Committee
Role
RoleTerm (authority = RULIB)
outside member
Name (type = corporate)
NamePart
Rutgers University
Role
RoleTerm (authority = RULIB)
degree grantor
Name (type = corporate)
NamePart
School of Health Professions
Role
RoleTerm (authority = RULIB)
school
TypeOfResource
Text
Genre (authority = marcgt)
theses
OriginInfo
DateCreated (encoding = w3cdtf); (keyDate = yes); (qualifier = exact)
2020
DateOther (encoding = w3cdtf); (qualifier = exact); (type = degree)
2020-08
Language
LanguageTerm (authority = ISO 639-3:2007); (type = text)
English
Abstract
Nephrolithiasis, or kidney stones, impose a significant burden of disease in the United States and come with considerable costs, pain and morbidity. The exact cause of stone formation is undefined, but formation is a process. Risk factors include environmental, diabetes, obesity, metabolic syndromes, low fluid intake, dehydration, diet, inflammatory bowel disorders, irritable bowel syndrome and genetics. Laboratory testing and appropriate diagnostic imaging studies are two key components of assessment and prevention.

This is a retrospective, quantitative study utilizing the Healthcare Cost and Utilization Project’s (HCUP) National Emergency Department Sample (NEDS) existing databases from 2012 to 2014 to classify outcomes for nephrolithiasis patients. ICD-9-CM, billing codes related to nephrolithiasis, relevant medical imaging exams, and procedural and surgical billing codes for interventions and procedures were selected. Descriptive statistical analyses as well as multiple regression models, were used to analyze frequencies and percentages of variables, the relationship of the data, identification of co-linearity amongst variables, and to predict outcomes.

The study sample includes a total of 509,192 emergency department (ED) visits for nephrolithiasis from 2012 to 2014 and reveals that IBS patients are two times more likely to require intervention. Stepwise regression models yield P-values of 0.004 for gender; 0.017 and 0.018 for minor diagnostic procedures; 0.006 and 0.001 for minor therapeutic procedures; 0.000 and 0.001 for major therapeutic procedures when predicting for total cost of care, and have a statistically significant impact on patient outcomes of nephrolithiasis.

This research offers an investigation of the prevalence of nephrolithiasis based on age, gender, and co-morbidity, specifically Irritable Bowel Syndrome, and is the first to report on patient outcomes. This analysis also provides clinicians with recommendations to utilize for a comprehensive assessment of nephrolithiasis patients in the ED.
Subject (authority = local)
Topic
Nephrolithiasis
Subject (authority = RUETD)
Topic
Biomedical Informatics
RelatedItem (type = host)
TitleInfo
Title
Rutgers University Electronic Theses and Dissertations
Identifier (type = RULIB)
ETD
Identifier
ETD_11060
PhysicalDescription
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application/pdf
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text/xml
Extent
1 online resource (viii, 60 pages)
Note (type = degree)
Ph.D.
Note (type = bibliography)
Includes bibliographical references
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TitleInfo
Title
School of Health Professions ETD Collection
Identifier (type = local)
rucore10007400001
Location
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NjNbRU
Identifier (type = doi)
doi:10.7282/t3-9m8f-4z33
Genre (authority = ExL-Esploro)
ETD doctoral
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Rights

RightsDeclaration (ID = rulibRdec0006)
The author owns the copyright to this work.
RightsHolder (type = personal)
Name
FamilyName
Stewart
GivenName
Kori
Role
Copyright Holder
RightsEvent
Type
Permission or license
DateTime (encoding = w3cdtf); (qualifier = exact); (point = start)
2020-07-27 11:51:04
AssociatedEntity
Name
Kori Stewart
Role
Copyright holder
Affiliation
Rutgers University. School of Health Professions
AssociatedObject
Type
License
Name
Author Agreement License
Detail
I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
Copyright
Status
Copyright protected
Availability
Status
Open
Reason
Permission or license
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Technical

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2020-08-02T14:08:39
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2020-08-02T14:08:41
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