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Repair Schwann cells: bridging the gap for successful nerve repair in the PNS

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TitleInfo
Title
Repair Schwann cells: bridging the gap for successful nerve repair in the PNS
Name (type = personal)
NamePart (type = family)
Gilmore
NamePart (type = given)
Evan
NamePart (type = date)
1993
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Evan Gilmore
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RoleTerm (authority = RULIB); (type = text)
author
Name (type = personal)
NamePart (type = family)
Kim
NamePart (type = given)
Haesun
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Haesun Kim
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Advisory Committee
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RoleTerm (authority = RULIB)
chair
Name (type = personal)
NamePart (type = family)
Bonder
NamePart (type = given)
Edward
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Edward Bonder
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Advisory Committee
Role
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internal member
Name (type = corporate)
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Rutgers University
Role
RoleTerm (authority = RULIB)
degree grantor
Name (type = corporate)
NamePart
Graduate School - Newark
Role
RoleTerm (authority = RULIB)
school
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Text
Genre (authority = marcgt)
theses
OriginInfo
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2021
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2021-01
Language
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English
Abstract
Peripheral nerve injuries remain a very prominent issue in today’s society all over the world, and can be sustained while working with machinery, playing sports or simply driving. Our current knowledge of the topic has limited applications for medical professionals in regards to treatments and surgeries they can perform to allow a patient to regain function in the nerve, which clearly leaves room for drastic improvement. Some organisms like mice and other murine species have demonstrated an ability to enact a Schwann cell facilitated nerve repair program that not all other organisms demonstrate when inflicted with a peripheral nerve injury particularly a severed nerve. As it stands our current comprehension of how organisms like these respond to peripheral nerve injuries on a cellular/molecular level is not complete and is still developing, but by studying these organisms over several decades we have made significant progress in the endeavor regardless. This review will discuss the known differences in nerve repair programs in human and mice, the most studied molecules and their molecular pathways that initiate the nerve repair program based on some of the most recently published literature on the topic and what we can take away from nerve injury models to develop future treatments and surgeries.
Subject (authority = RUETD)
Topic
Biology
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Rutgers University Electronic Theses and Dissertations
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ETD
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ETD_11392
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application/pdf
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Extent
1 online resource (vii, 69 pages)
Note (type = degree)
M.S.
Note (type = bibliography)
Includes bibliographical references
Genre (authority = ExL-Esploro)
ETD graduate
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TitleInfo
Title
Graduate School - Newark Electronic Theses and Dissertations
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rucore10002600001
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NjNbRU
Identifier (type = doi)
doi:10.7282/t3-bxjd-rs09
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Rights

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The author owns the copyright to this work.
RightsHolder (type = personal)
Name
FamilyName
Gilmore
GivenName
Evan
Role
Copyright Holder
RightsEvent
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Permission or license
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2020-12-27 15:46:19
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Name
Evan Gilmore
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Copyright holder
Affiliation
Rutgers University. Graduate School - Newark
AssociatedObject
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Author Agreement License
Detail
I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
Copyright
Status
Copyright protected
Availability
Status
Open
Reason
Permission or license
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Technical

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2021-01-07T21:18:45
DateCreated (point = end); (encoding = w3cdtf); (qualifier = exact)
2021-01-07T21:18:45
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