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Patient age, diagnosis, hemoglobin level and sex in the optimal management of blood and blood products
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Andoh, Cephas. Patient age, diagnosis, hemoglobin level and sex in the optimal management of blood and blood products. Retrieved from https://doi.org/doi:10.7282/t3-4s65-8940

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TitlePatient age, diagnosis, hemoglobin level and sex in the optimal management of blood and blood products
NameAndoh, Cephas (author); Coffman, Frederick (chair); Srinivasan, Shankar (co-chair); Feliz, Brad (outside member); Rutgers University; School of Health Professions
Date Created2021
Other Date2021-05 (degree)
SubjectAcute kidney failure, Biomedical Informatics
Extent1 online resource (x, 132 pages)
DescriptionBlood is a critically important human tissue, and for over a century, blood transfusions have saved the lives of countless patients. However, blood is often in short supply, and the cost of screening donated blood for immune compatibility and an ever-increasing number of blood-borne pathogens keeps rising. As healthcare systems search for ways to cut costs, it is appropriate to search for safe and effective ways to conserve blood and blood products.

Aim: This study will examine the following questions:
1. What is the relationship between the diagnosis and the amount of packed red blood cells (PRBC) used for patients with specific conditions?
2. What is the benefit of the transfusion for the patient in terms of the post transfusion hemoglobin and the clinical outcome?
3. Is there an association between patient age, diagnosis and the amount PRBC used? 4. What common diagnoses usually result in patients being given transfusions, and what is the clinical benefit of those transfusions?
The overall aim of this study is to identify conditions in which blood may be conserved, without affecting patient clinical outcomes.
Methodology: All patient data were collected from the Meditech database of the Queen of Valley Medical Center (QVMC), with the permission of the Blood bank supervisor and Medical Laboratory Director.
Results: Data was collected on 504 PRBC-transfused patients with various clinical conditions, who had critical pre-transfusion hemoglobin levels. Post-transfusion hemoglobin levels were examined at the time of patient discharge or patient death. A control cohort of twenty patients with the same conditions and critical hemoglobin levels but were not transfused due to religious or other reasons was also analyzed. Patients with acute kidney failure (AKF) and acute post-hemorrhagic anemia (APA) had better outcomes when they were transfused. The importance of any single transfusion to relapsed acute myeloid leukemia patients (AL) was difficult to assess as they are constantly being transfused. Patients with anemia of unknown causes (AU) and hemoglobin levels between 7-8g/dl did not require transfusion for survival.

Conclusion: Low hemoglobin levels alone should not automatically trigger transfusions. Disease type, patient age, and other factors should be taken into consideration.
NotePh.D.
NoteIncludes bibliographical references
Genretheses, ETD doctoral
Persistent URLhttps://doi.org/doi:10.7282/t3-4s65-8940
LanguageEnglish
CollectionSchool of Health Professions ETD Collection
Organization NameRutgers, The State University of New Jersey
RightsThe author owns the copyright to this work.
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