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Tools from statistical physics for systems biology and for genomics
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Descriptive

TypeOfResource
Text
TitleInfo (ID = T-1)
Title
Tools from statistical physics for systems biology and for genomics
Identifier
ETD_2813
Identifier (type = hdl)
http://hdl.rutgers.edu/1782.1/rucore10001600001.ETD.000056286
Language
LanguageTerm (authority = ISO639-2); (type = code)
eng
Genre (authority = marcgt)
theses
Subject (ID = SBJ-1); (authority = RUETD)
Topic
Physics and Astronomy
Subject (ID = SBJ-2); (authority = ETD-LCSH)
Topic
Genomics--Research
Subject (ID = SBJ-3); (authority = ETD-LCSH)
Topic
Stochastic analysis
Abstract (type = abstract)
My graduate studies involved three broad classes of problems, each of which are presented in different chapters of this thesis. The first two parts of my work were related to studying dynamics of biochemical networks. I studied a mean-field/stochastic model of epigenetic chromatin silencing in yeast. The model gives rise to different dynamical behaviors possible within the same molecular model and provides qualitative predictions that are being investigated experimentally. In another part of my work, I studied a model of segment polarity network in Drosophila and analyzed the parameter space of the system. I particularly studied the relation between the geometry of parameter space and the robustness of the network. I will show that, in addition to the volume, the geometry of this region has important consequences for the robustness and the fragility of a network. A major part of my PhD work involved applications of high-throughput sequencing technologies for extracting information at the genomic level. I present SOPRA, a new algorithm for exploiting the mate pair information for assembly of short reads. I have successfully applied SOPRA to real data and were able to assemble scaffolds of significant length with very few errors introduced in the process.
PhysicalDescription
Form (authority = gmd)
electronic resource
Extent
viii, 148 p. : ill.
InternetMediaType
application/pdf
InternetMediaType
text/xml
Note (type = degree)
Ph.D.
Note (type = bibliography)
Includes bibliographical references
Note (type = vita)
Includes vita
Note (type = statement of responsibility)
by Adel Dayarian
Name (ID = NAME-1); (type = personal)
NamePart (type = family)
Dayarian
NamePart (type = given)
Adel
NamePart (type = date)
1982-
Role
RoleTerm (authority = RULIB)
author
DisplayForm
Adel Dayarian
Name (ID = NAME-2); (type = personal)
NamePart (type = family)
Sengupta
NamePart (type = given)
Anirvan
Role
RoleTerm (authority = RULIB)
chair
Affiliation
Advisory Committee
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Anirvan Sengupta
Name (ID = NAME-3); (type = personal)
NamePart (type = family)
Baker
NamePart (type = given)
Andrew J
Role
RoleTerm (authority = RULIB)
internal member
Affiliation
Advisory Committee
DisplayForm
Andrew J Baker
Name (ID = NAME-4); (type = personal)
NamePart (type = family)
Bhanot
NamePart (type = given)
Gyan
Role
RoleTerm (authority = RULIB)
internal member
Affiliation
Advisory Committee
DisplayForm
Gyan Bhanot
Name (ID = NAME-5); (type = personal)
NamePart (type = family)
Andrei
NamePart (type = given)
Eva
Role
RoleTerm (authority = RULIB)
internal member
Affiliation
Advisory Committee
DisplayForm
Eva Andrei
Name (ID = NAME-6); (type = personal)
NamePart (type = family)
Stolovitzky
NamePart (type = given)
Gustavo
Role
RoleTerm (authority = RULIB)
outside member
Affiliation
Advisory Committee
DisplayForm
Gustavo Stolovitzky
Name (ID = NAME-1); (type = corporate)
NamePart
Rutgers University
Role
RoleTerm (authority = RULIB)
degree grantor
Name (ID = NAME-2); (type = corporate)
NamePart
Graduate School - New Brunswick
Role
RoleTerm (authority = RULIB)
school
OriginInfo
DateCreated (qualifier = exact)
2010
DateOther (qualifier = exact); (type = degree)
2010
Place
PlaceTerm (type = code)
xx
RelatedItem (type = host)
TitleInfo
Title
Rutgers University Electronic Theses and Dissertations
Identifier (type = RULIB)
ETD
RelatedItem (type = host)
TitleInfo
Title
Graduate School - New Brunswick Electronic Theses and Dissertations
Identifier (type = local)
rucore19991600001
Location
PhysicalLocation (authority = marcorg); (displayLabel = Rutgers, The State University of New Jersey)
NjNbRU
Identifier (type = doi)
doi:10.7282/T33X86CS
Genre (authority = ExL-Esploro)
ETD doctoral
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Rights

RightsDeclaration (AUTHORITY = GS); (ID = rulibRdec0006)
The author owns the copyright to this work.
Copyright
Status
Copyright protected
Availability
Status
Open
Reason
Permission or license
RightsHolder (ID = PRH-1); (type = personal)
Name
FamilyName
Dayarian
GivenName
Adel
Role
Copyright Holder
RightsEvent (ID = RE-1); (AUTHORITY = rulib)
Type
Permission or license
DateTime
2010-08-16 17:29:39
AssociatedEntity (ID = AE-1); (AUTHORITY = rulib)
Role
Copyright holder
Name
Adel Dayarian
Affiliation
Rutgers University. Graduate School - New Brunswick
AssociatedObject (ID = AO-1); (AUTHORITY = rulib)
Type
License
Name
Author Agreement License
Detail
I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
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Technical

ContentModel
ETD
MimeType (TYPE = file)
application/pdf
MimeType (TYPE = container)
application/x-tar
FileSize (UNIT = bytes)
22538240
Checksum (METHOD = SHA1)
982c8e4163e9ffb627914ed6e39d01871b3a0dd8
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