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Childhood abuse and physiological dysregulation in midlife and old age
Descriptive
TitleInfo
Title
Childhood abuse and physiological dysregulation in midlife and old age
Name
(type = personal)
NamePart
(type = family)
Lee
NamePart
(type = given)
Chioun
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Chioun Lee
Role
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(authority = RULIB)
author
Name
(type = personal)
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(type = family)
Carr
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(type = given)
Deborah
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Deborah Carr
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Advisory Committee
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chair
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(type = family)
White
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(type = given)
Helene R
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Helene R White
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Advisory Committee
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internal member
Name
(type = personal)
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(type = family)
Horwitz
NamePart
(type = given)
Allan
DisplayForm
Allan Horwitz
Affiliation
Advisory Committee
Role
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(authority = RULIB)
internal member
Name
(type = personal)
NamePart
(type = family)
Springer
NamePart
(type = given)
Kristen W
DisplayForm
Kristen W Springer
Affiliation
Advisory Committee
Role
RoleTerm
(authority = RULIB)
internal member
Name
(type = personal)
NamePart
(type = family)
Kusnecov
NamePart
(type = given)
Alexander
DisplayForm
Alexander Kusnecov
Affiliation
Advisory Committee
Role
RoleTerm
(authority = RULIB)
outside member
Name
(type = corporate)
NamePart
Rutgers University
Role
RoleTerm
(authority = RULIB)
degree grantor
Name
(type = corporate)
NamePart
Graduate School - New Brunswick
Role
RoleTerm
(authority = RULIB)
school
TypeOfResource
Text
Genre
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theses
OriginInfo
DateCreated
(qualifier = exact)
2012
DateOther
(qualifier = exact);
(type = degree)
2012-10
CopyrightDate
(qualifier = exact)
2012
Place
PlaceTerm
(type = code)
xx
Language
LanguageTerm
(authority = ISO639-2b);
(type = code)
eng
Abstract
(type = abstract)
The overarching goal of my research is to incorporate sociological perspectives (the life course perspective, inequality theory) with biomedical knowledge (stress theory) to document midlife and old age health for victims of childhood abuse. Using data from the National Survey of Midlife Development in the U.S. (MIDUS), I explore the extent to which childhood abuse creates physiological dysregulation and chronic diseases: cortisol abnormality (Chapter 2), metabolic syndrome (MetS) (Chapter 3), elevated markers of inflammation (Chapter 4), and three immune-related disorders (asthma, allergies, arthritis) (Chapter 2). I then explore the extent to which these associations are explained by three potential mediators: behavioral risk factors (sleeping and eating problems, body mass index [BMI]), perceived stress, and social relationship quality (Chapters 3-4). I also investigate whether profiles of childhood abuse and the pathways linking abuse to MetS differ by gender (Chapter 3). Finally, I assess whether the effects of childhood abuse on inflammatory markers vary by age group (Chapter 4). I find five distinct classes of childhood abuse for the full sample and for women and four for men. Women are more likely than men to report frequent emotional and sexual abuse. Childhood abuse is associated with low cortisol levels and immune-related disorders. Low levels of cortisol partially mediate the association between abuse and both allergies and arthritis. Some abuse subgroups are at greater risk of MetS than the no abuse subgroup. For women, frequent sexual abuse increases the risk of MetS; this association is not statistically significant among men. The associations between abuse and inflammatory markers vary by age. In the younger age groups (ages 34-44 and 45-54), the levels of inflammatory markers for victims are higher than non-victims; there are no statistically significant differences in the older age groups (ages 55-64 and 65-84). Victims are at greater risk of mortality, suggesting that selective mortality might contribute to the reduced gap in the older age cohorts. High BMI, sleep problems, and weak or strained family ties partially mediate the association. Overall, my project demonstrates how integrating sociological perspectives and biomedical knowledge illuminates the associations between early life adversity and lifelong health consequences.
Subject
(authority = RUETD)
Topic
Sociology
RelatedItem
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TitleInfo
Title
Rutgers University Electronic Theses and Dissertations
Identifier
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ETD
Identifier
ETD_4188
PhysicalDescription
Form
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electronic resource
InternetMediaType
application/pdf
InternetMediaType
text/xml
Extent
xii, 168 p. : ill.
Note
(type = degree)
Ph.D.
Note
(type = bibliography)
Includes bibliographical references
Note
(type = vita)
Includes vita
Note
(type = statement of responsibility)
by Chioun Lee
Subject
(authority = ETD-LCSH)
Topic
Adult child abuse victims--Health and hygiene--United States
Subject
(authority = ETD-LCSH)
Topic
Adult child abuse victims--Mental health--United States
Subject
(authority = ETD-LCSH)
Topic
Child abuse--Health aspects--United States
Subject
(authority = ETD-LCSH)
Topic
Stress (Psychology)
Identifier
(type = hdl)
http://hdl.rutgers.edu/1782.1/rucore10001600001.ETD.000066886
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TitleInfo
Title
Graduate School - New Brunswick Electronic Theses and Dissertations
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rucore19991600001
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NjNbRU
Identifier
(type = doi)
doi:10.7282/T39W0D8D
Genre
(authority = ExL-Esploro)
ETD doctoral
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Rights
RightsDeclaration
(ID = rulibRdec0006)
The author owns the copyright to this work.
RightsHolder
(type = personal)
Name
FamilyName
Lee
GivenName
Chioun
Role
Copyright Holder
RightsEvent
Type
Permission or license
DateTime
(encoding = w3cdtf);
(qualifier = exact);
(point = start)
2012-08-07 10:05:49
AssociatedEntity
Name
Chioun Lee
Role
Copyright holder
Affiliation
Rutgers University. Graduate School - New Brunswick
AssociatedObject
Type
License
Name
Author Agreement License
Detail
I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
Copyright
Status
Copyright protected
Availability
Status
Open
Reason
Permission or license
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