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Changes in nucleus accumbens core firing patterns during reward-related events
Descriptive
TitleInfo
Title
Changes in nucleus accumbens core firing patterns during reward-related events
Name
(type = personal)
NamePart
(type = family)
Ma
NamePart
(type = given)
Sisi
NamePart
(type = date)
1985-
DisplayForm
Sisi Ma
Role
RoleTerm
(authority = RULIB)
author
Name
(type = personal)
NamePart
(type = family)
West
NamePart
(type = given)
Mark
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Mark West
Affiliation
Advisory Committee
Role
RoleTerm
(authority = RULIB)
chair
Name
(type = personal)
NamePart
(type = family)
Vicario
NamePart
(type = given)
David
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David Vicario
Affiliation
Advisory Committee
Role
RoleTerm
(authority = RULIB)
internal member
Name
(type = personal)
NamePart
(type = family)
McGann
NamePart
(type = given)
John
DisplayForm
John McGann
Affiliation
Advisory Committee
Role
RoleTerm
(authority = RULIB)
internal member
Name
(type = personal)
NamePart
(type = family)
Horvitz
NamePart
(type = given)
Jon
DisplayForm
Jon Horvitz
Affiliation
Advisory Committee
Role
RoleTerm
(authority = RULIB)
outside member
Name
(type = corporate)
NamePart
Rutgers University
Role
RoleTerm
(authority = RULIB)
degree grantor
Name
(type = corporate)
NamePart
Graduate School - New Brunswick
Role
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(authority = RULIB)
school
TypeOfResource
Text
Genre
(authority = marcgt)
theses
OriginInfo
DateCreated
(qualifier = exact)
2014
DateOther
(qualifier = exact);
(type = degree)
2014-05
Place
PlaceTerm
(type = code)
xx
Language
LanguageTerm
(authority = ISO639-2b);
(type = code)
eng
Abstract
(type = abstract)
Learning is characterized by the ability to appropriately respond to external cues that predict rewarding or aversive outcomes. The nucleus accumbens is a key mediator of reward prediction and reward-related behaviors. However, it is not well understood how accumbens neurons acquire and maintain their responsiveness to these events. In the present study, 56 nucleus accumbens core neurons were electrophysiologically recorded over 10 sessions when the animals were trained in a conditioning paradigm. Changes in firing rates of core neurons were analyzed over training days during the following events: reward cue presentation, cued and non-cued approaches towards the reward, reward consumption and reward seeking. As a population, core neurons displayed an increase in firing rate in response to presentation of the reward predicting auditory cue. The latency of core activity in response to the auditory cue was significantly reduced after animals acquired the task. Increased firing rates were also observed during approach behaviors following the onset of cue, but not
Subject
(authority = RUETD)
Topic
Psychology
RelatedItem
(type = host)
TitleInfo
Title
Rutgers University Electronic Theses and Dissertations
Identifier
(type = RULIB)
ETD
Identifier
ETD_5505
PhysicalDescription
Form
(authority = gmd)
electronic resource
InternetMediaType
application/pdf
InternetMediaType
text/xml
Extent
vii, 61 p. : ill.
Note
(type = degree)
Ph.D.
Note
(type = bibliography)
Includes bibliographical references
Note
(type = statement of responsibility)
by Sisi Ma
Subject
(authority = ETD-LCSH)
Topic
Nucleus accumbens
Subject
(authority = ETD-LCSH)
Topic
Neurons
Subject
(authority = ETD-LCSH)
Topic
Learning
RelatedItem
(type = host)
TitleInfo
Title
Graduate School - New Brunswick Electronic Theses and Dissertations
Identifier
(type = local)
rucore19991600001
Location
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(authority = marcorg);
(displayLabel = Rutgers, The State University of New Jersey)
NjNbRU
Identifier
(type = doi)
doi:10.7282/T3RJ4GS2
Genre
(authority = ExL-Esploro)
ETD doctoral
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Rights
RightsDeclaration
(ID = rulibRdec0006)
The author owns the copyright to this work.
RightsHolder
(type = personal)
Name
FamilyName
Ma
GivenName
Sisi
Role
Copyright Holder
RightsEvent
Type
Permission or license
DateTime
(encoding = w3cdtf);
(qualifier = exact);
(point = start)
2014-04-14 16:18:41
AssociatedEntity
Name
Sisi Ma
Role
Copyright holder
Affiliation
Rutgers University. Graduate School - New Brunswick
AssociatedObject
Type
License
Name
Author Agreement License
Detail
I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
RightsEvent
DateTime
(encoding = w3cdtf);
(qualifier = exact);
(point = start)
2014-05-31
DateTime
(encoding = w3cdtf);
(qualifier = exact);
(point = end)
2015-05-31
Type
Embargo
Detail
Access to this PDF has been restricted at the author's request. It will be publicly available after May 31st, 2015.
Copyright
Status
Copyright protected
Availability
Status
Open
Reason
Permission or license
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Technical
RULTechMD
(ID = TECHNICAL1)
ContentModel
ETD
OperatingSystem
(VERSION = 5.1)
windows xp
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Statistical Profile