Comparison between early and late stage lung cancer in relation to cost and mortality
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Harding, Kathleen A..
Comparison between early and late stage lung cancer in relation to cost and mortality. Retrieved from
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TitleComparison between early and late stage lung cancer in relation to cost and mortality
Date Created2016
Other Date2016-10 (degree)
Extent1 online resource (xiii, 209 p. : ill.)
DescriptionLung cancer (LC) is a life threatening disease associated with significant cost and high mortality. LC is diagnosed in either early stage or more frequently in late stage, the face of lung cancer. Objective: To make a comparison between early and late stage lung cancer (SLC) in relation to cost and mortality Methods: The study is a random effects data analysis of a historical dataset the Nationwide Inpatient Sample (NIS). The study is based on the time period 2002, 2006 and 2011. The primary outcomes of interest is cost (total cost per day) and mortality (died/did not die). Two replicates samples for the years 2002, 2006 and 2011 were taken. Demographic factors that influence cost and mortality were co-varied out of the analysis. Descriptive Statistical analysis and bivariate analysis were done for cost includes ANOVA and ANCOVA. A statistical analysis for mortality includes logistic regression. Cost and mortality for early versus late (SLC) were measured in isolation and after accounting for age, gender, race, socio-economic status, number of diagnoses, length of stay, and number of procedures.Results: In the three years, 3 samples of 2173, 13,032, and 15,771 including 3 replicate samples of 2060, 13,032 and 15,772 participated in the study. All significant relationships tested at an alpha level of (P<0.05). The cost for early (SLC) was higher compared to late (SLC) and is statistically significant. The number of procedures in part accounted for the difference. Late (SLC) had higher mortality compared to early (SLC) and is statistically significant. The number of diagnoses in part accounted for the difference. The study showed early (SLC) costs 14% more than late (SLC). Late stage is more deadly, however, the gap is surprisingly small at 30% or an odds ratio of 1.3 to 1.5 after adjusting for covariates. Conclusion: This study of HCUP data revealed that early (SLC) is more expensive than late (SLC). Additionally, the data revealed that mortality is higher in late (SLC) compared to early (SLC). Overall, these finding highlight the important role of Health Informatics in understanding the cost and mortality of early and late (SLC).
NotePh.D.
NoteIncludes bibliographical references
Noteby Kathleen A. Harding
Genretheses, ETD doctoral
Languageeng
CollectionSchool of Health Related Professions ETD Collection
Organization NameRutgers, The State University of New Jersey
RightsThe author owns the copyright to this work.
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