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The relationship of COMT, working memory, and fluid intelligence in humans
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Zacher, Douglas N.. The relationship of COMT, working memory, and fluid intelligence in humans. Retrieved from https://doi.org/doi:10.7282/T3JS9SCV

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TitleThe relationship of COMT, working memory, and fluid intelligence in humans
NameZacher, Douglas N. (author); Whitlow, Jesse W (chair); Bravo, Mary (internal member); van der Wel, Robrecht (internal member); Rutgers University; Camden Graduate School
Date Created2015
Other Date2015-10 (degree)
SubjectPsychology, Short-term memory, Dopamine
Extent1 online resource (iii, 25 p. : ill.)
DescriptionThe role of dopamine in working memory and fluid intelligence is well documented. Dopamine in the frontal cortex is evidenced to exert influence over working memory. Dopamine synthesis is evidenced to be associated with fluid intelligence. Catechol-o-methyltransferase is a gene responsible for large quantities of dopamine in the frontal cortex. The genetic polymorphism on COMT is known to reduce the amount of dopamine that is destroyed through enzymatic degradation in the frontal lobe by four times the normal amount. We hypothesized that the COMT MET allele will be associated positively with increased working memory capacity and fluid intelligence whereas the COMT VAL allele will not be. We also hypothesized that due to the shared neural processes, working memory capacity and fluid intelligence will be correlated with one another. We found significant correlations between the WMC battery and the fluid intelligence measure however we found no relationship between the COMT polymorphisms, working memory capacity, and fluid intelligence.
NoteM.A.
NoteIncludes bibliographical references
Noteby Douglas N. Zacher
Genretheses, ETD graduate
Persistent URLhttps://doi.org/doi:10.7282/T3JS9SCV
Languageeng
CollectionCamden Graduate School Electronic Theses and Dissertations
Organization NameRutgers, The State University of New Jersey
RightsThe author owns the copyright to this work.
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