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The relationship of COMT, working memory, and fluid intelligence in humans
Descriptive
TitleInfo
Title
The relationship of COMT, working memory, and fluid intelligence in humans
Name
(type = personal)
NamePart
(type = family)
Zacher
NamePart
(type = given)
Douglas N.
NamePart
(type = date)
1989-
DisplayForm
Douglas N. Zacher
Role
RoleTerm
(authority = RULIB)
author
Name
(type = personal)
NamePart
(type = family)
Whitlow
NamePart
(type = given)
Jesse W
DisplayForm
Jesse W Whitlow
Affiliation
Advisory Committee
Role
RoleTerm
(authority = RULIB)
chair
Name
(type = personal)
NamePart
(type = family)
Bravo
NamePart
(type = given)
Mary
DisplayForm
Mary Bravo
Affiliation
Advisory Committee
Role
RoleTerm
(authority = RULIB)
internal member
Name
(type = personal)
NamePart
(type = family)
van der Wel
NamePart
(type = given)
Robrecht
DisplayForm
Robrecht van der Wel
Affiliation
Advisory Committee
Role
RoleTerm
(authority = RULIB)
internal member
Name
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NamePart
Rutgers University
Role
RoleTerm
(authority = RULIB)
degree grantor
Name
(type = corporate)
NamePart
Camden Graduate School
Role
RoleTerm
(authority = RULIB)
school
TypeOfResource
Text
Genre
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theses
OriginInfo
DateCreated
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(qualifier = exact)
2015
DateOther
(qualifier = exact);
(type = degree)
2015-10
CopyrightDate
(encoding = w3cdtf);
(qualifier = exact)
2015
Place
PlaceTerm
(type = code)
xx
Language
LanguageTerm
(authority = ISO639-2b);
(type = code)
eng
Abstract
(type = abstract)
The role of dopamine in working memory and fluid intelligence is well documented. Dopamine in the frontal cortex is evidenced to exert influence over working memory. Dopamine synthesis is evidenced to be associated with fluid intelligence. Catechol-o-methyltransferase is a gene responsible for large quantities of dopamine in the frontal cortex. The genetic polymorphism on COMT is known to reduce the amount of dopamine that is destroyed through enzymatic degradation in the frontal lobe by four times the normal amount. We hypothesized that the COMT MET allele will be associated positively with increased working memory capacity and fluid intelligence whereas the COMT VAL allele will not be. We also hypothesized that due to the shared neural processes, working memory capacity and fluid intelligence will be correlated with one another. We found significant correlations between the WMC battery and the fluid intelligence measure however we found no relationship between the COMT polymorphisms, working memory capacity, and fluid intelligence.
Subject
(authority = RUETD)
Topic
Psychology
Subject
(authority = ETD-LCSH)
Topic
Short-term memory
Subject
(authority = ETD-LCSH)
Topic
Dopamine
RelatedItem
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TitleInfo
Title
Rutgers University Electronic Theses and Dissertations
Identifier
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ETD
Identifier
ETD_6707
PhysicalDescription
Form
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electronic resource
InternetMediaType
application/pdf
InternetMediaType
text/xml
Extent
1 online resource (iii, 25 p. : ill.)
Note
(type = degree)
M.A.
Note
(type = bibliography)
Includes bibliographical references
Note
(type = statement of responsibility)
by Douglas N. Zacher
RelatedItem
(type = host)
TitleInfo
Title
Camden Graduate School Electronic Theses and Dissertations
Identifier
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rucore10005600001
Location
PhysicalLocation
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(displayLabel = Rutgers, The State University of New Jersey)
NjNbRU
Identifier
(type = doi)
doi:10.7282/T3JS9SCV
Genre
(authority = ExL-Esploro)
ETD graduate
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Rights
RightsDeclaration
(ID = rulibRdec0006)
The author owns the copyright to this work.
RightsHolder
(type = personal)
Name
FamilyName
Zacher
GivenName
Douglas
MiddleName
N.
Role
Copyright Holder
RightsEvent
Type
Permission or license
DateTime
(encoding = w3cdtf);
(qualifier = exact);
(point = start)
2015-09-04 13:13:25
AssociatedEntity
Name
Douglas Zacher
Role
Copyright holder
Affiliation
Rutgers University. Camden Graduate School
AssociatedObject
Type
License
Name
Author Agreement License
Detail
I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
Copyright
Status
Copyright protected
Availability
Status
Open
Reason
Permission or license
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Technical
RULTechMD
(ID = TECHNICAL1)
ContentModel
ETD
OperatingSystem
(VERSION = 5.1)
windows xp
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