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The effectiveness of telephone counseling on treatment-related symptoms and health-related quality of life (HRQOL) in patients with chronic hepatitis C undergoing oral direct acting antiviral non-interferon-based treatment
Descriptive
TitleInfo
Title
The effectiveness of telephone counseling on treatment-related symptoms and health-related quality of life (HRQOL) in patients with chronic hepatitis C undergoing oral direct acting antiviral non-interferon-based treatment
Name
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Watkins
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Natalia
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1956-
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Natalia Watkins
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author
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Holly
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Cheryl
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Cheryl Holly
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Advisory Committee
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chair
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Kamienski
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Mary
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Mary Kamienski
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Advisory Committee
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internal member
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Rutgers University
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degree grantor
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School of Nursing - RBHS
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school
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Text
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theses
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2019
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2019-10
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English
Abstract
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Background: Hepatitis C, a viral borne disease, affects between 3 to 4 million people in the United States. Although some people carry the hepatitis C virus without their knowledge or any ill effects, the disease can be life-threatening, progressing to chronic hepatitis C (CHC), cirrhosis, or liver cancer. New treatments, such as oral, Direct Acting Antiviral (DAA) non-interferon based (non-INF) treatments can positively address these issues, but they can also lead to untoward symptoms that can affect patients’ health related quality of life (HRQOL).
Purpose: The purpose of this project was to explore the effectiveness of telephone counseling, perceived treatment-related symptoms, and the HRQOL of patients with chronic hepatitis C (CHC) before, during and after treatment of oral DAA non IFN treatments.
Method: Data from the SF 36 were collected using the Statistical Package of Social Sciences (SPSS). A t-test was used for analysis to compare data from the first administered with the second, which showed a comparison of HRQOL at the beginning and end of the study, that is, before and after telephone counseling. Data collected from the de novo survey that ascertained treatment-related symptoms were individually assessed before, during, and after completion of the regimen treatment. Non-parametric Friedman's ANOVA procedures were conducted to determine whether symptom severity changed across time using mean ranks.
Findings: Telephone counseling had a positive influence on symptoms management and improvement in participants' HRQOL. Statistical analyses showed that reduction in fatigue and headache scoring at the end of the treatment promoted a higher quality of life in patients with hepatitis C. There was improvement in bodily pain, functional activities increased with the corresponding reduction in severity of headache and depression, and in some cases a full resolution of symptoms of fatigue.
Conclusions: Telephone counseling had a positive influence on symptoms management and improvement in participants' HRQOL. The results of this project showed that telephone counseling helped participants to achieve better well-being through the management of treatment related symptoms and recognize the benefits and barriers that block the change in behavior
Purpose: The purpose of this project was to explore the effectiveness of telephone counseling, perceived treatment-related symptoms, and the HRQOL of patients with chronic hepatitis C (CHC) before, during and after treatment of oral DAA non IFN treatments.
Method: Data from the SF 36 were collected using the Statistical Package of Social Sciences (SPSS). A t-test was used for analysis to compare data from the first administered with the second, which showed a comparison of HRQOL at the beginning and end of the study, that is, before and after telephone counseling. Data collected from the de novo survey that ascertained treatment-related symptoms were individually assessed before, during, and after completion of the regimen treatment. Non-parametric Friedman's ANOVA procedures were conducted to determine whether symptom severity changed across time using mean ranks.
Findings: Telephone counseling had a positive influence on symptoms management and improvement in participants' HRQOL. Statistical analyses showed that reduction in fatigue and headache scoring at the end of the treatment promoted a higher quality of life in patients with hepatitis C. There was improvement in bodily pain, functional activities increased with the corresponding reduction in severity of headache and depression, and in some cases a full resolution of symptoms of fatigue.
Conclusions: Telephone counseling had a positive influence on symptoms management and improvement in participants' HRQOL. The results of this project showed that telephone counseling helped participants to achieve better well-being through the management of treatment related symptoms and recognize the benefits and barriers that block the change in behavior
Subject
(authority = RUETD)
Topic
Post-Master's DNP Practice
Subject
(authority = local)
Topic
Telephone counseling
Subject
(authority = LCSH)
Topic
Health counseling
Subject
(authority = LCSH)
Topic
Hepatitis C -- Patients -- Counseling
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Rutgers University Electronic Theses and Dissertations
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ETD_10239
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1 online resource (48 pages) : illustrations
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DNP
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Includes bibliographical references
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School of Nursing (RBHS) DNP Projects
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rucore10004500001
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doi:10.7282/t3-gbhp-gd43
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ETD doctoral
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The author owns the copyright to this work.
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Watkins
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Natalia
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Permission or license
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2019-09-12 20:16:19
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Natalia Watkins
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Rutgers University. School of Nursing - RBHS
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I hereby grant to the Rutgers University Libraries and to my school the non-exclusive right to archive, reproduce and distribute my thesis or dissertation, in whole or in part, and/or my abstract, in whole or in part, in and from an electronic format, subject to the release date subsequently stipulated in this submittal form and approved by my school. I represent and stipulate that the thesis or dissertation and its abstract are my original work, that they do not infringe or violate any rights of others, and that I make these grants as the sole owner of the rights to my thesis or dissertation and its abstract. I represent that I have obtained written permissions, when necessary, from the owner(s) of each third party copyrighted matter to be included in my thesis or dissertation and will supply copies of such upon request by my school. I acknowledge that RU ETD and my school will not distribute my thesis or dissertation or its abstract if, in their reasonable judgment, they believe all such rights have not been secured. I acknowledge that I retain ownership rights to the copyright of my work. I also retain the right to use all or part of this thesis or dissertation in future works, such as articles or books.
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Embargo
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2019-10-31
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2099-12-31
Detail
Access to this PDF has been restricted at the author's request.
Copyright
Status
Copyright protected
Availability
Status
Open
Reason
Permission or license
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