DescriptionContinued high relapse rates following SUDs treatment urges examination of aspects of SUDs which are currently undertreated. There are currently two theories on the development and maintenance of SUDs which offer valuable insight but are underutilized in informing treatment. One theory comes from personality science and views SUDs as hyperactivity of the behavioral activation system (BAS) combined with hypoactivity in the behavioral inhibition system (BIS). The second theory derives from the cognitive branch of psychology and states that low working memory capacity (WMC) is a primary contributor to the development of SUDs. The present paper demonstrates how these two theories intersect to form one unified theory for the conceptualization and treatment of SUDs. The present paper demonstrates that both high-BAS/low-BIS and WMC result in the same behavioral pattern which is observed in individuals with SUDs: impulsivity, the overvaluation of rewards, and the undervaluation of punishment. To improve treatment outcomes for SUDs, future developments in treatment need to target these behaviors.