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Stem cell therapy combined with CRISPR to engineer anti-inflammatory chondrocytes to improve neuroinflammation in rheumatoid arthritis
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Gary, LaKeshia. Stem cell therapy combined with CRISPR to engineer anti-inflammatory chondrocytes to improve neuroinflammation in rheumatoid arthritis. Retrieved from https://doi.org/doi:10.7282/t3-4pmc-1b91

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TitleStem cell therapy combined with CRISPR to engineer anti-inflammatory chondrocytes to improve neuroinflammation in rheumatoid arthritis
NameGary, LaKeshia (author); Fried, Nathan (chair); Saidel, William (internal member); Dunaev, Jamie (internal member); Laws, Kaitlin (outside member); Rutgers University; Camden Graduate School
Date Created2020
Other Date2020-10 (degree)
SubjectCRISPR (Genetics), Biology
Extent1 online resource (vi, 33 pages)
DescriptionRegenerative medicine has the potential to improve several medical issues, such as tissue damage, diminished cell maintenance/repair and failed organ systems. CRISPR technology provides the opportunity to expand stem cell therapy to not only replace lost cells, but also genetically engineer them to treat certain conditions. Rheumatoid arthritis is one disorder where combining both therapies can improve the patient outcome by genetically engineering replacement chondrocytes to constitutively release anti-inflammatory cytokines. This unique strategy presents the opportunity to not only target the pain produced from joint deterioration, but also continuously replace the cartilage to increase the reduced mobility of Rheumatoid Arthritis diagnosed patients.
NoteM.S.
NoteIncludes bibliographical references
Genretheses, ETD graduate
Persistent URLhttps://doi.org/doi:10.7282/t3-4pmc-1b91
LanguageEnglish
CollectionCamden Graduate School Electronic Theses and Dissertations
Organization NameRutgers, The State University of New Jersey
RightsThe author owns the copyright to this work.
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